Safety and Long-Term Efficacy of Drug-Coated Balloon Angioplasty following Rotational Atherectomy for Severely Calcified Coronary Lesions Compared with New Generation Drug-Eluting Stents

التفاصيل البيبلوغرافية
العنوان:	Safety and Long-Term Efficacy of Drug-Coated Balloon Angioplasty following Rotational Atherectomy for Severely Calcified Coronary Lesions Compared with New Generation Drug-Eluting Stents
المؤلفون:	Katsumi Ueno, Norihiko Morita, Yoshinobu Kojima, Hiroshi Takahashi, Masanori Kawasaki, Ryuta Ito, Hiroki Kondo, Shingo Minatoguchi, Tamami Yoshida, Yasumasa Hashimoto, Tomohiko Tatsumi, Tomoya Kitamura
المصدر:	Journal of Interventional Cardiology, Vol 2019 (2019)
بيانات النشر:	Hindawi-Wiley, 2019.
سنة النشر:	2019
المجموعة:	LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية:	Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف:	Objectives. This study sought to assess the safety and long-term efficacy of drug-coated balloons (DCB) following aggressive intracoronary image-guided rotational atherectomy (iRA) for severe coronary artery calcification (CAC), and to compare this strategy with new generation drug-eluting stents (nDES) following iRA. Background. Ischemic events following the treatment of CAC is still relatively high. Thus, more innovative strategies are required. Methods. We evaluated 123 consecutive patients (166 lesions) with de novo CAC undergoing an iRA (burr size; 0.7 of the mean reference diameter by intracoronary imaging) followed by DCB (DCB-iRA; 54 patients, 68 lesions) or nDES (nDES-iRA; 69 patients, 98 lesions). Follow-up angiography was obtained at > 6 months. Results. The target vessels (right coronary and circumflex), bifurcation (67.6% versus 47.9%), reference diameter (2.28mm versus 2.49mm), and lesion length (11.89mm versus 18.78mm) were significantly different between the two groups. The median follow-up was 732 days. TLR and TVR in DCB-iRA and nDES-iRA at 3 years were similar: 15.6% versus 16.3% (P=0.99) and 15.6% versus 23.3% (P=0.38). In 41 well-matched lesion pairs after propensity score analysis, the cumulative incidence of TLR and TVR in DCB-iRA and nDES-iRA at 3 years was 12.9% versus 16.3% (P=0.70) and 12.9% versus 26.1% (P=0.17), respectively. On QCA analysis, although the acute gain was smaller in DCB-iRA (0.85 mm versus 1.53 mm, P
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	0896-4327 1540-8183
Relation:	https://doaj.org/toc/0896-4327; https://doaj.org/toc/1540-8183
DOI:	10.1155/2019/9094178
URL الوصول:	https://doaj.org/article/e7739912c3b04db387a4df364a6ee32b
رقم الانضمام:	edsdoj.7739912c3b04db387a4df364a6ee32b
قاعدة البيانات:	Directory of Open Access Journals

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الوصف
تدمد:	08964327 15408183
DOI:	10.1155/2019/9094178