التفاصيل البيبلوغرافية
| العنوان: |
Efficacy and safety of selective internal radiation therapy with yttrium-90 for the treatment of unresectable hepatocellular carcinoma |
| المؤلفون: |
Nguyen Van Thai, Nguyen Tien Thinh, Thai Doan Ky, Mai Hong Bang, Dinh Truong Giang, Le Ngoc Ha, Mai Hong Son, Dao Duc Tien, Hyun Woong Lee |
| المصدر: |
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-9 (2021) |
| بيانات النشر: |
BMC, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: |
Hepatocellular carcinoma, Selective internal radiation therapy, Yttrium-90, Survival, Tumor response, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: |
Abstract Background This retrospective analysis was undertaken to evaluate the efficiency of SIRT with Y-90 microspheres and determined prognostic factors affecting patients with unresectable HCC. Methods A total of 97 patients diagnosed with unresectable HCC who underwent SIRT with Y-90 microspheres. Patient survival was assessed using the Kaplan–Meier method, and prognostic factors affecting survival were assessed using log-rank tests and Cox proportional hazards regression. Results Among the 97 patients (90 males, mean age 60.4 ± 12.3 years) who underwent SIRT, the median clinical follow-up was 16.4 (1.8–62) months. The median overall survival (OS) was 23.9 ± 2.4 months. Tumor response according to the Modified RECIST in patients followed up beyond 6 months included a complete response (CR) to treatment in 12 patients (18.8%), partial response (PR) in 23 (35.8%), stable disease (SD) in 8 (12.5%), and progressive disease (PD) in 21 (32.8%). Factors associated with longer OS included age > 65 years, BCLC stage B, tumor size |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1471-230X |
| Relation: |
https://doaj.org/toc/1471-230X |
| DOI: |
10.1186/s12876-021-01805-6 |
| URL الوصول: |
https://doaj.org/article/7374d5ca4a934584a7342de30f57d50b |
| رقم الانضمام: |
edsdoj.7374d5ca4a934584a7342de30f57d50b |
| قاعدة البيانات: |
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