Academic Journal

Association Between Single Nucleotide Polymorphisms in PPARA and EPAS1 Genes and High-Altitude Appetite Loss in Chinese Young Men

التفاصيل البيبلوغرافية
العنوان: Association Between Single Nucleotide Polymorphisms in PPARA and EPAS1 Genes and High-Altitude Appetite Loss in Chinese Young Men
المؤلفون: Wenxu Pan, Chuan Liu, Jihang Zhang, Xubin Gao, Shiyong Yu, Hu Tan, Jie Yu, Dehui Qian, Jiabei Li, Shizhu Bian, Jie Yang, Chen Zhang, Lan Huang, Jun Jin
المصدر: Frontiers in Physiology, Vol 10 (2019)
بيانات النشر: Frontiers Media S.A., 2019.
سنة النشر: 2019
المجموعة: LCC:Physiology
مصطلحات موضوعية: high altitude, appetite loss, hypoxia, PPARA, EPAS1, single nucleotide polymorphism, Physiology, QP1-981
الوصف: Appetite loss is a common symptom that occurs in high altitude (HA) for lowlanders. Previous studies indicated that hypoxia is the initiating vital factor of HA appetite loss. PPARA, EPAS1, EGLN1, HIF1A, HIF1AN, and NFE2L2 play important roles in hypoxic responses. We aimed to explore the association of these hypoxia-related gene polymorphisms with HA appetite loss. In this study, we enrolled 416 young men who rapidly ascended to Lhasa (3700 m) from Chengdu (
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1664-042X
Relation: https://www.frontiersin.org/article/10.3389/fphys.2019.00059/full; https://doaj.org/toc/1664-042X
DOI: 10.3389/fphys.2019.00059
URL الوصول: https://doaj.org/article/7199e7d0253a4f6f98f4a6cb27080b1d
رقم الانضمام: edsdoj.7199e7d0253a4f6f98f4a6cb27080b1d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1664042X
DOI:10.3389/fphys.2019.00059