التفاصيل البيبلوغرافية
| العنوان: |
Ketamine as the main analgesic agent during analgesia-based sedation for elective colonoscopy – A randomised, double-blind, control study |
| المؤلفون: |
Mirza Kovačević, Nermina Rizvanović, Adisa Šabanović Adilović, Jasmina Smajić, Selma Sijerčić |
| المصدر: |
Saudi Journal of Anaesthesia, Vol 16, Iss 4, Pp 423-429 (2022) |
| بيانات النشر: |
Wolters Kluwer Medknow Publications, 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Anesthesiology |
| مصطلحات موضوعية: |
analgesic, colonoscopy, fentanyl, ketamine, Anesthesiology, RD78.3-87.3 |
| الوصف: |
Aim: The aim of the study was to compare the analgesic effects of ketamine over fentanyl combined with propofol in analgesia-based elective colonoscopy with purpose of patient safety and satisfaction. Methods: This is a double-blinded prospective randomized controlled trial. Ninety patients were included and randomized to either fentanyl-propofol (Group FP, n: 30), ketamine-propofol (Group KP, n: 30) or propofol-control group (Group C, n: 30). Group FP patients received fentanyl and propofol, Group KP received ketamine and propofol and Group C, propofol. In all groups, incremental doses of propofol were used to maintain a Ramsay sedation score (RSS) of 5. Respiratory depression and hemodynamic parameters were monitored for the first minute and every 5 min during endoscopy. Fifteen minutes after the procedure, the degree of pain was assessed using a visual analog scale (VAS), the quality of recovery according to the Aldrete score (ARS), complications during and after the procedure and additional doses of propofol were recorded. Results: Mean arterial pressure (MAP) at 5 and 30 min (p < 0.05), heart rate (HR) at 15, 25 and 30 min (p < 0.05) and peripheral oxygen saturation (SpO2) at 30 min (p < 0.05) were statistically significant for Group FP. Desaturation (*p = 0.033), and weakness (*p = 0.004) was also significant for Group FP at 20, 25 and 30 min (p < 0.05). Pain was lower assessed for the Group KP according to the VAS (**p = 0.025). Conclusion: In analgesia-based colonoscopy, ketamine provides appropriate analgesia and less incidence of complications compared to fentanyl. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1658-354X |
| Relation: |
http://www.saudija.org/article.asp?issn=1658-354X;year=2022;volume=16;issue=4;spage=423;epage=429;aulast=Kovačević; https://doaj.org/toc/1658-354X |
| DOI: |
10.4103/sja.sja_488_22 |
| URL الوصول: |
https://doaj.org/article/70c6e2e1347142d0bad6d59db31b690c |
| رقم الانضمام: |
edsdoj.70c6e2e1347142d0bad6d59db31b690c |
| قاعدة البيانات: |
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