Academic Journal
Ultrasound super-resolution imaging for non-invasive assessment of microvessel in prostate lesion
العنوان: | Ultrasound super-resolution imaging for non-invasive assessment of microvessel in prostate lesion |
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المؤلفون: | Xin Huang, Huarong Ye, Yugang Hu, Yumeng Lei, Yi Tian, Xingyue Huang, Jun Zhang, Yao Zhang, Bin Gui, Qianhui Liu, Ge Zhang, Qing Deng |
المصدر: | Cancer Imaging, Vol 25, Iss 1, Pp 1-9 (2025) |
بيانات النشر: | BMC, 2025. |
سنة النشر: | 2025 |
المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: | Prostate lesion, Ultasound super-resolution imaging, Microvessel, Non-invasive diagnosis, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: | Abstract Background Prostate cancer (PCa) is the leading cause of cancer-related morbidity and mortality in men worldwide. An early and accurate diagnosis is crucial for effective treatment and prognosis. Traditional invasive procedures such as image-guided prostate biopsy often cause discomfort and complications, deterring some patients from undergoing these necessary tests. This study aimed to explore the feasibility and clinical value of using ultrasound super-resolution imaging (US SRI) for non-invasively assessing the microvessel characteristics of prostate lesion. Methods This study included 127 patients with prostate lesion who presented at Renmin Hospital of Wuhan University between November 2023 and June 2024 were included in this study. All the patients underwent transrectal US (TRUS), contrast-enhanced US (CEUS), and US SRI. CEUS parameters of time-intensity curve (TIC): arrival time (AT), rising time (RT), time to peak (TTP), peak intensity (PKI), falling time (FT), mean transit time (MTT), ascending slope (AS), descending slope (DS), D/A slope ratio (SR), and area under the TIC (AUC). US SRI parameters: microvessel density (MVD), microvessel diameter (D), microvessel velocity (V), microvessel tortuosity (T), and fractal number (FN), were analyzed and compared between prostate benign and malignant lesion. Results The tumor markers of prostate in the malignant group were all higher than those in the benign group, and the differences were statistically significant (P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1470-7330 |
Relation: | https://doaj.org/toc/1470-7330 |
DOI: | 10.1186/s40644-024-00819-z |
URL الوصول: | https://doaj.org/article/702be5d980ee4de9980652f76fbd0f3a |
رقم الانضمام: | edsdoj.702be5d980ee4de9980652f76fbd0f3a |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14707330 |
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DOI: | 10.1186/s40644-024-00819-z |