التفاصيل البيبلوغرافية
| العنوان: |
New developments in immunotherapy for lymphoma |
| المؤلفون: |
Benjamin Heyman, Yiping Yang |
| المصدر: |
Cancer Biology & Medicine, Vol 15, Iss 3, Pp 189-209 (2018) |
| بيانات النشر: |
China Anti-Cancer Association, 2018. |
| سنة النشر: |
2018 |
| المجموعة: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: |
CAR-T cells, immune checkpoint blockade, bispecific antibodies, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: |
The development of immunotherapies for lymphoma has undergone a revolutionary evolution over the past decades. Since the advent of rituximab as the first successful immunotherapy for B-cell non-Hodgkin lymphoma over two decades ago, a plethora of new immunotherapeutic approaches to treat lymphoma has ensued. Four of the most exciting classes of immunotherapies include: chimeric antigen receptor T-cells, bispecific antibodies, immune checkpoint inhibitors, and vaccines. However, with addition of these novel therapies the appropriate timing of treatment, optimal patient population, duration of therapy, toxicity, and cost must be considered. In this review, we describe the most-promising immunotherapeutic approaches for the treatment of lymphoma in clinical development, specifically focusing on clinical trials performed to date and strategies for improvement. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2095-3941 |
| Relation: |
http://www.cancerbiomed.org/index.php/cocr/article/view/1176; https://doaj.org/toc/2095-3941 |
| DOI: |
10.20892/j.issn.2095-3941.2018.0037 |
| URL الوصول: |
https://doaj.org/article/d6edb19c132440e18ddb7b00f84d1fee |
| رقم الانضمام: |
edsdoj.6edb19c132440e18ddb7b00f84d1fee |
| قاعدة البيانات: |
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