Academic Journal

Low Serum Cholinesterase Identifies Patients With Worse Outcome and Increased Mortality After TIPS

التفاصيل البيبلوغرافية
العنوان: Low Serum Cholinesterase Identifies Patients With Worse Outcome and Increased Mortality After TIPS
المؤلفون: Lena Stockhoff, Theresa Muellner‐Bucsics, Antoaneta A. Markova, Marie Schultalbers, Simone A. Keimburg, Tammo L. Tergast, Jan B. Hinrichs, Nicolas Simon, Svetlana Gerbel, Michael P. Manns, Mattias Mandorfer, Markus Cornberg, Bernhard C. Meyer, Heiner Wedemeyer, Thomas Reiberger, Benjamin Maasoumy
المصدر: Hepatology Communications, Vol 6, Iss 3, Pp 621-632 (2022)
بيانات النشر: Wolters Kluwer Health/LWW, 2022.
سنة النشر: 2022
المجموعة: LCC:Diseases of the digestive system. Gastroenterology
مصطلحات موضوعية: Diseases of the digestive system. Gastroenterology, RC799-869
الوصف: Transjugular intrahepatic portosystemic shunt (TIPS) is an effective treatment for portal hypertension‐related complications. However, careful selection of patients is crucial. The aim of this study was to evaluate the prognostic value of serum cholinesterase (CHE) for outcomes and mortality after TIPS insertion. In this multicenter study, 389 consecutive patients with cirrhosis receiving a TIPS at Hannover Medical School, University Hospital Essen, or Medical University of Vienna were included. The Hannover cohort (n = 200) was used to initially explore the role of CHE, whereas patients from Essen and Vienna served as a validation cohort (n = 189). Median age of the patients was 58 years and median Model for End‐Stage Liver Disease (MELD) score was 12. Multivariable analysis identified MELD score (hazard ratio [HR]: 1.16; P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2471-254X
Relation: https://doaj.org/toc/2471-254X
DOI: 10.1002/hep4.1829
URL الوصول: https://doaj.org/article/ae6e93fd54f64b7e95f7f25c2792aacf
رقم الانضمام: edsdoj.6e93fd54f64b7e95f7f25c2792aacf
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:2471254X
DOI:10.1002/hep4.1829