التفاصيل البيبلوغرافية
| العنوان: |
Gorham–Stout disease or new entity on the basis of vasculopathy |
| المؤلفون: |
H. Hasan Yeter |
| المصدر: |
Alexandria Journal of Medicine, Vol 53, Iss 2, Pp 193-196 (2017) |
| بيانات النشر: |
Taylor & Francis Group, 2017. |
| سنة النشر: |
2017 |
| المجموعة: |
LCC:Medicine |
| مصطلحات موضوعية: |
Gorham–Stout disease, Vanishing bone disease, Vasculitis, Thrombosis, Medicine |
| الوصف: |
Gorham–Stout disease (GSD) is a rare osteolytic bone disease also known as vanishing bone disease. The pathogenesis of GSD is not well understood. Studies showed that lymphatic and blood endothelial cells in addition to macrophages secrete TNFα and IL-6 that stimulate osteoclast formation with osteolysis. Also TNFα secretion inhibits osteoblast differentiation and new bone formation. It is known that cytokines such as TNFα, IL-1 and complement system activation are responsible for inflammation and necrosis in the vessel wall at vasculitis. Both diseases have similar pathogenesis. Here, we presented a case of Gorham’s disease with involvement of bilateral humerus, systemic arterial thrombosis and mesenteric vasculitis. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2090-5068 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2090506816300148; https://doaj.org/toc/2090-5068 |
| DOI: |
10.1016/j.ajme.2016.03.006 |
| URL الوصول: |
https://doaj.org/article/6db959374ac14e1ca0a0ecc6895da8cd |
| رقم الانضمام: |
edsdoj.6db959374ac14e1ca0a0ecc6895da8cd |
| قاعدة البيانات: |
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