التفاصيل البيبلوغرافية
| العنوان: |
Equivalent Long-term Transplantation Outcomes for Kidneys Donated After Brain Death and Cardiac Death: Conclusions From a Nationwide Evaluation |
| المؤلفون: |
Alexander Schaapherder, Leonie G.M. Wijermars, Dorottya K. de Vries, Aiko P.J. de Vries, Frederike J. Bemelman, Jacqueline van de Wetering, Arjan D. van Zuilen, Maarten H.L. Christiaans, Luuk H. Hilbrands, Marije C. Baas, Azam S. Nurmohamed, Stefan P. Berger, Ian P. Alwayn, Esther Bastiaannet, Jan H.N. Lindeman |
| المصدر: |
EClinicalMedicine, Vol 4, Iss , Pp 25-31 (2018) |
| بيانات النشر: |
Elsevier, 2018. |
| سنة النشر: |
2018 |
| المجموعة: |
LCC:Medicine (General) |
| مصطلحات موضوعية: |
Medicine (General), R5-920 |
| الوصف: |
Background: Despite growing waiting lists for renal transplants, hesitations persist with regard to the use of deceased after cardiac death (DCD) renal grafts. We evaluated the outcomes of DCD donations in The Netherlands, the country with the highest proportion of DCD procedures (42.9%) to test whether these hesitations are justified. Methods: This study included all procedures with grafts donated after brain death (DBD) (n = 3611) and cardiac death (n = 2711) performed between 2000 and 2017. Transplant outcomes were compared by Kaplan Meier and Cox regression analysis, and factors associated with short (within 90 days of transplantation) and long-term graft loss evaluated in multi-variable analyses. Findings: Despite higher incidences of early graft loss (+50%) and delayed graft function (+250%) in DCD grafts, 10-year graft and recipient survival were similar for the two graft types (Combined 10-year graft survival: 73.9% (95% CI: 72.5–75.2), combined recipient survival: 64.5% (95 CI: 63.0–66.0%)). Long-term outcome equivalence was explained by a reduced impact of delayed graft function on DCD graft survival (RR: 0.69 (95% CI: 0.55–0.87), p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2589-5370 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2589537018300324; https://doaj.org/toc/2589-5370 |
| DOI: |
10.1016/j.eclinm.2018.09.007 |
| URL الوصول: |
https://doaj.org/article/d6d7e4a54b094108833a819883c04728 |
| رقم الانضمام: |
edsdoj.6d7e4a54b094108833a819883c04728 |
| قاعدة البيانات: |
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