Academic Journal
CircRNAs: A promising target for intervention regarding glycolysis in gastric cancer
| العنوان: | CircRNAs: A promising target for intervention regarding glycolysis in gastric cancer |
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| المؤلفون: | Qian Dai, Yulin Liu, Fanghui Ding, Rong Guo, Gang Cheng, Hua Wang |
| المصدر: | Heliyon, Vol 10, Iss 14, Pp e34658- (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Science (General) LCC:Social sciences (General) |
| مصطلحات موضوعية: | Gastric cancer, Glycolysis, Warburg effect, CircRNA, miRNA, Science (General), Q1-390, Social sciences (General), H1-99 |
| الوصف: | Gastric cancer is characterized by a high incidence and mortality rate, with therapeutic efficacy currently constrained by substantial limitations. Aerobic glycolysis in cancer constitutes a pivotal aspect of the reprogramming of energy metabolism in tumor cells and profoundly influences the malignant progression of cancer. CircRNAs, serving as stable endogenous RNA, have been shown to regulate downstream targets by sponging miRNAs, which in turn are involved in the regulation of multiple malignant behaviors in a variety of cancers through the CircRNA-miRNA axis, suggesting that CircRNAs could be used as potential therapeutic targets for cancer. In recent years, it has been shown that some CircRNAs can be involved in the regulation of GC glycolysis, therefore, this paper summarizes the notable roles of some important CircRNAs in the regulation of GC glycolysis in recent years, which may be useful for our understanding of GC progression and the development of new therapeutic strategies. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2405-8440 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2405844024106895; https://doaj.org/toc/2405-8440 |
| DOI: | 10.1016/j.heliyon.2024.e34658 |
| URL الوصول: | https://doaj.org/article/6d60a65dd20941979acb6e406057165a |
| رقم الانضمام: | edsdoj.6d60a65dd20941979acb6e406057165a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24058440 |
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| DOI: | 10.1016/j.heliyon.2024.e34658 |