Academic Journal

Triglyceride levels are ethnic-specifically associated with an index of stearoyl-CoA desaturase activity and n-3 PUFA levels in Asians

التفاصيل البيبلوغرافية
العنوان: Triglyceride levels are ethnic-specifically associated with an index of stearoyl-CoA desaturase activity and n-3 PUFA levels in Asians
المؤلفون: Kuninori Shiwaku, Michio Hashimoto, Keiko Kitajima, Akiko Nogi, Erdembileg Anuurad, Byambaa Enkhmaa, Jung-Man Kim, In-Shik Kim, Sung-Kook Lee, Tsendsuren Oyunsuren, Osamu Shido, Yosuke Yamane
المصدر: Journal of Lipid Research, Vol 45, Iss 5, Pp 914-922 (2004)
بيانات النشر: Elsevier, 2004.
سنة النشر: 2004
المجموعة: LCC:Biochemistry
مصطلحات موضوعية: fish, stearoyl coenzyme A, n-3 polyunsaturated fatty acid, Biochemistry, QD415-436
الوصف: Accumulated evidence suggests that hypertriglyceridemia (HTG) is independently associated with an increased incidence of cardiovascular disease. The hypotriglyceridemic effects of n-3 PUFAs have been confirmed in Caucasians, but the effect in Asians is less clear. Recent evidence indicates that stearoyl-CoA desaturase (SCD) activity induced with high-carbohydrate diets increases plasma triglyceride levels. We investigated the relationship between triglyceride levels and the ratio of plasma oleic acid to stearic acid (the 18:1/18:0 ratio), a plasma marker of SCD activity, and n-3 PUFAs in 411 Japanese, 418 Korean, and 251 Mongolian adults. The Japanese and Koreans had higher values for triglyceride than their Mongolian counterparts, despite lower body mass index values for the Japanese and Koreans. The Japanese and Koreans ate fish more frequently and had remarkably higher values for n-3 PUFAs than did the Mongolians. Multiple regression analysis showed that triglyceride levels had a great magnitude of correlation with the increases in 18:1/18:0 ratio for the Japanese and Mongolians, and n-3 PUFAs remained significant for the Mongolians.HTG is ethnicity-specifically associated with an increase in the 18:1/18:0 ratio and a decrease in n-3 PUFA in plasma for Japanese, Koreans, and Mongolians.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0022-2275
Relation: http://www.sciencedirect.com/science/article/pii/S0022227520318320; https://doaj.org/toc/0022-2275
DOI: 10.1194/jlr.M300483-JLR200
URL الوصول: https://doaj.org/article/6c1d1ef9368d4663a1c87c1b810e824f
رقم الانضمام: edsdoj.6c1d1ef9368d4663a1c87c1b810e824f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:00222275
DOI:10.1194/jlr.M300483-JLR200