Academic Journal
The activity of different extracts from Panax quinquefolium L. cultures against pathogenic Staphylococcus aureus with respect to ginsenoside content
| العنوان: | The activity of different extracts from Panax quinquefolium L. cultures against pathogenic Staphylococcus aureus with respect to ginsenoside content |
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| المؤلفون: | Sienkiewicz Monika, Głowacka Anna, Kowalczyk Edward, Kochan Ewa |
| المصدر: | Archives of Biological Sciences, Vol 67, Iss 4, Pp 1277-1284 (2015) |
| بيانات النشر: | University of Belgrade, University of Novi Sad, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Biology (General) |
| مصطلحات موضوعية: | antibacterial effect, minimal inhibitory concentration, plant secondary metabolites, Biology (General), QH301-705.5 |
| الوصف: | Ginsenosides can be isolated from various cultures of Panax quinquefolium L., American ginseng. The aim of the study was to determine the antibacterial activity of extracts from leaves, stalks, hairy root cultures and field roots of P. quinquefolium L. containing ginsenosides against Staphylococcus aureus isolates obtained from various clinical materials. The agar well diffusion assay was used to evaluate microbial growth inhibition at various concentrations of extracts. The susceptibility of the clinical isolates to recommended antibiotics was determined with the disk-diffusion method. The results showed that the tested extracts inhibited the growth of all S. aureus clinical isolates, including MRSA (methicillin-resistant S. aureus) with MIC values ranging from 0.5 mg/mL to 1.7 mg/mL. The level of antimicrobial activity of extracts depends on the ginsenoside content. Both field roots and hairy root cultures represent excellent sources of these metabolites. Extracts with ginsenosides were found to inhibit multidrug-resistant staphylococci and can be a valuable complement to antistaphylococcal therapy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0354-4664 1821-4339 |
| Relation: | https://doaj.org/toc/0354-4664; https://doaj.org/toc/1821-4339 |
| DOI: | 10.2298/ABS150330104S |
| URL الوصول: | https://doaj.org/article/c691c157713d4257abe9b35876a3cb30 |
| رقم الانضمام: | edsdoj.691c157713d4257abe9b35876a3cb30 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03544664 18214339 |
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| DOI: | 10.2298/ABS150330104S |