التفاصيل البيبلوغرافية
| العنوان: |
Improvements of visual function and outer retinal morphology following spontaneous regression of cancer in anti-recoverin cancer-associated retinopathy |
| المؤلفون: |
Yuka Suimon, Wataru Saito, Kiriko Hirooka, Atsuhiro Kanda, Hidenori Kitai, Jun Sakakibara-Konishi, Susumu Ishida |
| المصدر: |
American Journal of Ophthalmology Case Reports, Vol 5, Iss C, Pp 137-140 (2017) |
| بيانات النشر: |
Elsevier, 2017. |
| سنة النشر: |
2017 |
| المجموعة: |
LCC:Ophthalmology |
| مصطلحات موضوعية: |
Cancer-associated retinopathy, Outer retinal morphology, Recoverin, Spontaneous regression of cancer, Visual function, Ophthalmology, RE1-994 |
| الوصف: |
Purpose: To report an anti-recoverin antibody-positive cancer-associated retinopathy (anti-recoverin CAR) patient with remarkable improvements of visual function and outer retinal morphology following spontaneous regression of cancer. Observations: A 65-year-old woman with small cell lung carcinoma developed progressive, bilateral vision loss with diffuse loss of the ellipsoid zone at the macula on optical coherence tomography and marked reduced responses of a- and b-waves on electroretinography. Western blot analysis led to a diagnosis of anti-recoverin CAR. The visual function and outer retinal morphology gradually improved following spontaneous regression of the cancer and the initiation of systemic corticosteroid. Subsequent intermittent chemotherapy and continuation of corticosteroid maintained reduction of the cancer and prevented the recurrence of CAR, with preservation of improvements of the visual function and macular outer retinal morphology. Conclusions and importance: These results suggest that requirement for obtaining good visual prognosis in CAR patients is to make the cancer regress prior to falling into photoreceptor apotosis. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2451-9936 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2451993616301906; https://doaj.org/toc/2451-9936 |
| DOI: |
10.1016/j.ajoc.2016.12.024 |
| URL الوصول: |
https://doaj.org/article/68f981a263e4451a9afa609a2e071acd |
| رقم الانضمام: |
edsdoj.68f981a263e4451a9afa609a2e071acd |
| قاعدة البيانات: |
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