Academic Journal
Long-term functional outcome and quality of life 2.5 years after thrombolysis in acute ischemic stroke
العنوان: | Long-term functional outcome and quality of life 2.5 years after thrombolysis in acute ischemic stroke |
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المؤلفون: | Marie Schäbitz, Leona Möller, Anja Friedrich, Nele Klein, Alkisti Kitsiou, Isabell Greeve, Anja Gerstner, Leonard Wulff, Wolf-Rüdiger Schäbitz, Lars Timmermann, Andreas Rogalewski |
المصدر: | Neurological Research and Practice, Vol 5, Iss 1, Pp 1-16 (2023) |
بيانات النشر: | BMC, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Neurosciences. Biological psychiatry. Neuropsychiatry LCC:Neurology. Diseases of the nervous system |
مصطلحات موضوعية: | Stroke, Thrombolysis, Long-term outcome, Quality of life, HRQoL, Modified Rankin Scale, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429 |
الوصف: | Abstract Background Evaluation of outcome after stroke is largely based on assessment of gross function 3 months after stroke onset using scales such as mRS. Cognitive or social functions, level of symptom burden or emotional health are not usually assessed, nor are data available on long-term functional outcomes years after stroke. Methods Analysis of 1141 patients with AIS treated with IVT from two major German university hospitals between 2017 and 2020. Patient characteristics and short-term outcome were analysed from patient records. Long-term outcome of 228 patients with prior written informed consent was assessed via telephone survey using mRS and PROMs (EQ-5D-5L, EQ-VAS) 2.5 years after stroke. Results Predictors of excellent to good long-term outcome were younger age, event to door time ≤ 2 h, NIHSS ≤ 6 on admission and NIHSS ≤ 6 after IVT. Stroke recurrence was a negative predictor. Predictors of excellent quality of life at 2.5 years included age |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2524-3489 |
Relation: | https://doaj.org/toc/2524-3489 |
DOI: | 10.1186/s42466-023-00291-3 |
URL الوصول: | https://doaj.org/article/d68f0a6dff5441329327d21aa5f8e35c |
رقم الانضمام: | edsdoj.68f0a6dff5441329327d21aa5f8e35c |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 25243489 |
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DOI: | 10.1186/s42466-023-00291-3 |