Academic Journal

VRE in cirrhotic patients

التفاصيل البيبلوغرافية
العنوان: VRE in cirrhotic patients
المؤلفون: Melissa Barger, Emily Blodget, Sol Pena, Wendy Mack, Tse-Ling Fong
المصدر: BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-8 (2019)
بيانات النشر: BMC, 2019.
سنة النشر: 2019
المجموعة: LCC:Infectious and parasitic diseases
مصطلحات موضوعية: Vancomycin-resistant enterococcus, Cirrhosis, Liver disease, Infectious and parasitic diseases, RC109-216
الوصف: Abstract Background Vancomycin resistant enterococci (VRE) infections are of increasing concern in many hospitalized patients. Patients with cirrhosis are at added risk of infection with VRE, with associated increased risk for complications from infections. The goals of this study were to: [1] identify risk factors for VRE amongst cirrhotic patients before liver transplantation, and [2] evaluate risk of morbidity and mortality at 30-days and one-year after VRE infection. Methods Chart review of 533 cirrhotic patients hospitalized at a tertiary medical center was performed. Patients infected with VRE (n = 65) were separately compared to patients infected with gram-negative organisms (n = 80) and uninfected patients (n = 306). Results In multivariable logistic regression analyses, female gender (OR 3.73(95% CI1.64,8.49)), severity of liver disease measured by higher Child Pugh scores (OR 0.37(95%CI 0.16,0.84)), presence of ascites (OR 9.43(95% CI 3.22,27.65) and any type of dialysis (OR 3.31,95% CI (1.21,9.04), oral antibiotic prophylaxis for spontaneous bacterial peritonitis and rifaximin use were statistically significantly associated with VRE infection (OR 2.37 (95%CI 1.27, 4.42)). VRE-infected patients had significantly longer mean ICU and total hospital stays (both p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2334
Relation: http://link.springer.com/article/10.1186/s12879-019-4352-1; https://doaj.org/toc/1471-2334
DOI: 10.1186/s12879-019-4352-1
URL الوصول: https://doaj.org/article/ae681c14eec448e0830aa5cf0eb17b1b
رقم الانضمام: edsdoj.681c14eec448e0830aa5cf0eb17b1b
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712334
DOI:10.1186/s12879-019-4352-1