Academic Journal
Larvicidal, cytotoxic and genotoxic effects of aqueous leaf extract of Jatropha mollissima (Pohl) Baill
| العنوان: | Larvicidal, cytotoxic and genotoxic effects of aqueous leaf extract of Jatropha mollissima (Pohl) Baill |
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| المؤلفون: | José Rafael Silva Araújo, Maria Wlly da Silva Costa, Wallace Baldez Oliveira, Reginaldo Roris Cavalcante, Pedro Marcos Almeida, Francielle Alline Martins |
| المصدر: | Acta Scientiarum: Biological Sciences, Vol 40, Iss 1 (2018) |
| بيانات النشر: | Universidade Estadual de Maringá, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Biology (General) LCC:Microbiology |
| مصطلحات موضوعية: | Aedes aegypti, Allium cepa test, chromosome alterations, medicinal plant., Biology (General), QH301-705.5, Microbiology, QR1-502 |
| الوصف: | The present study aimed to evaluate the larvicidal effect of aqueous leaf extract from Jatropha mollissima on the larvae of Aedes aegypti and analyze its cytotoxic and genotoxic activity in the Allium cepa test. Larvae of the mosquito were exposed to the negative and positive controls (distilled water and diflubenzuron, 0.003 mg mL-1, respectively) and to leaf extract concentrations of 0.001, 0.005, 0.01, 0.02, 0.04, 0.06, 0.08 and 0.1 mg mL-1. The mortality rate was evaluated every 24 hours over five days. For the cytotoxic and genotoxic analyses, roots of A. cepa were exposed to the negative (distilled water) and positive control (trifluralin, 0.84 ppm) and to different leaf extract concentrations (0.01, 0.1, 1 and 10 mg mL-1) for 24 hours. The statistical analyses were performed by Kruskal-Wallis test (p < 0.05). The leaf extract presented promising larvicidal activity at the concentrations of 0.08 and 0.1 mg mL-1, and none of the concentrations evaluated in A. cepa exhibited cytotoxic or genotoxic effect. Since the larvicidal action of J. mollissima and the absence of cellular toxicity have been demonstrated, further studies are recommended to determine the mechanism of action of the extract as a possible natural larvicide. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1679-9283 1807-863X |
| Relation: | https://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/34501; https://doaj.org/toc/1679-9283; https://doaj.org/toc/1807-863X |
| DOI: | 10.4025/actascibiolsci.v40i1.34501 |
| URL الوصول: | https://doaj.org/article/c678a3de69d24038842e0e205be7249a |
| رقم الانضمام: | edsdoj.678a3de69d24038842e0e205be7249a |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 16799283 1807863X |
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| DOI: | 10.4025/actascibiolsci.v40i1.34501 |