Academic Journal

PAX2, PAX8, and PR are correlated with ovarian seromucinous borderline tumor with endometriosis

التفاصيل البيبلوغرافية
العنوان: PAX2, PAX8, and PR are correlated with ovarian seromucinous borderline tumor with endometriosis
المؤلفون: Bo Seong Yun, Seyeon Won, Ju-Hyun Kim, Nara Lee, Miseon Kim, Mi Kyoung Kim, Mi-La Kim, Yong Wook Jung, Ji Young Kim, Seok Ju Seong, Eunah Shin
المصدر: Journal of Ovarian Research, Vol 15, Iss 1, Pp 1-8 (2022)
بيانات النشر: BMC, 2022.
سنة النشر: 2022
المجموعة: LCC:Gynecology and obstetrics
مصطلحات موضوعية: Borderline tumor, Seromucinous, Endometrioid, Endometriosis, PAX2, PAX8, Gynecology and obstetrics, RG1-991
الوصف: Abstract Background Ovarian “seromucinous carcinoma” has been recently removed in 2020 5th Edition of WHO classification of Female Genital Tumors and is considered as a subtype of endometrioid carcinoma with mucinous differentiation, while “seromucinous borderline tumor” remains and exists as a distinct entity. Both diseases may be considered as no more same lineage. However, ovarian seromucinous borderline tumor (SMBT) is also one of the endometriosis-related neoplasm of ovary similar to endometrioid tumor, featuring that about 50% of ovarian SMBTs combine endometriosis. The present study was aimed to investigate whether the ovarian SMBTs are different in clinical features and molecular patterns, according to the presence of combined endometriosis. Results There were no statistical differences in clinical findings between two groups. There was also no significant difference in pregnancy outcomes and recurrence between two groups. In immunohistochemical patterns, there was a statistically significant difference in PAX2 and PAX8 expression between in ovarian SMBT with or without endometriosis (P = 0.016, P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1757-2215
Relation: https://doaj.org/toc/1757-2215
DOI: 10.1186/s13048-022-00975-5
URL الوصول: https://doaj.org/article/671ffec916d145cbae6b56d109173c83
رقم الانضمام: edsdoj.671ffec916d145cbae6b56d109173c83
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17572215
DOI:10.1186/s13048-022-00975-5