التفاصيل البيبلوغرافية
| العنوان: |
Rare Presentation of Toxoplasma Pneumonitis in the Absence of Neurological Symptoms in an AIDS Patient and Use of Next-Generation Sequencing for Diagnosis |
| المؤلفون: |
Moni Roy, Nikhut Siddique, Bindu Bathina, Sharjeel Ahmad |
| المصدر: |
European Journal of Case Reports in Internal Medicine (2020) |
| بيانات النشر: |
SMC MEDIA SRL, 2020. |
| سنة النشر: |
2020 |
| المجموعة: |
LCC:Medicine |
| مصطلحات موضوعية: |
disseminated toxoplasmosis, toxoplasma pneumonitis, next-generation sequencing, hiv/aids, Medicine |
| الوصف: |
Toxoplasma gondii is a known cause of encephalitis in human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients. Toxoplasma pneumonitis is a manifestation of extracerebral toxoplasmosis and can be clinically indistinguishable from other opportunistic infections including Pneumocystis jirovecii pneumonia (PJP) and miliary tuberculosis. In this case report, Toxoplasma pneumonitis and disseminated toxoplasmosis was diagnosed using next-generation sequencing (NGS) and polymerase chain reaction (PCR) assessment. NGS can detect microbial cell-free DNA (cfDNA) circulating in the plasma of over 1,000 pathogens. This case is a rare presentation of Toxoplasma pneumonitis in the absence of neurological symptoms and we discuss the use of NGS of microbial cfDNA and PCR tests that may be utilized for the timely diagnosis of such challenging cases. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2284-2594 |
| Relation: |
https://www.ejcrim.com/index.php/EJCRIM/article/view/1862; https://doaj.org/toc/2284-2594 |
| DOI: |
10.12890/2020_001862 |
| URL الوصول: |
https://doaj.org/article/d66fe2e5b245415fae3bc96bf0cb805b |
| رقم الانضمام: |
edsdoj.66fe2e5b245415fae3bc96bf0cb805b |
| قاعدة البيانات: |
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