Academic Journal
Blood Count and Renal Functionality Assessments in the Emergency Section Disclose Morbidity and Mortality in Omicron COVID-19 Patients: A Retrospective Study
| العنوان: | Blood Count and Renal Functionality Assessments in the Emergency Section Disclose Morbidity and Mortality in Omicron COVID-19 Patients: A Retrospective Study |
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| المؤلفون: | Eqrem Rusi, Fiorenza Pennacchia, Wael Abu Ruqa, Maria Antonella Zingaropoli, Patrizia Pasculli, Giuseppina Talarico, Giuseppe Bruno, Christian Barbato, Antonio Minni, Luigi Tarani, Gioacchino Galardo, Francesco Pugliese, Marco Lucarelli, Maria Rosa Ciardi, Luigi Meucci, Giampiero Ferraguti, Marco Fiore |
| المصدر: | Clinics and Practice, Vol 14, Iss 3, Pp 685-702 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | SARS-CoV-2, mortality, morbidity, biomarkers, variant, blood analyses, Medicine (General), R5-920 |
| الوصف: | Background: SARS-CoV-2 is the coronavirus responsible for the COVID-19 pandemic. Even though we are no longer in a pandemic situation, people are still getting infected, some of them need hospitalization and a few of them die. Methods: We conducted a retrospective study including 445 patients who accessed the Emergency Section of Policlinico Umberto I, Rome, Italy, where they had routine blood exams. In this study, we focused on the complete blood count, serum creatinine and azotemia. The data were analyzed using ANOVA, Spearman correlation and ROC analyses. They were divided into four groups based on their clinical outcomes: (1) the emergency group (patients who had mild forms and were quickly discharged); (2) the hospital ward group (patients who were admitted to the emergency section and were then hospitalized in a COVID-19 ward); (3) the intensive care unit (ICU) group (patients who required intensive assistance after the admission in the emergency section); (4) the deceased group (patients who had a fatal outcome after admission to the emergency section). Results: We found significant changes for creatinine, azotemia, hematocrit, mean corpuscular hemoglobin concentration, basophils, monocytes, red blood cell distribution width, hemoglobin, hematocrit and red blood cell numbers using ANOVA according to their clinical outcomes, particularly for the deceased group. Also, we found linear correlations of clinical outcomes with eosinophils, hemoglobin, hematocrit, mean corpuscular hemoglobin concentration, lymphocyte, neutrophil, platelet and red blood cell number and red blood cell distribution width. Conclusions: This study discloses an early association between “classical” routine blood biomarkers and the severity of clinical outcomes in Omicron patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 14030055 2039-7283 |
| Relation: | https://www.mdpi.com/2039-7283/14/3/55; https://doaj.org/toc/2039-7283 |
| DOI: | 10.3390/clinpract14030055 |
| URL الوصول: | https://doaj.org/article/66d7529ef6c346bc941c9d407c5c5b8f |
| رقم الانضمام: | edsdoj.66d7529ef6c346bc941c9d407c5c5b8f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14030055 20397283 |
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| DOI: | 10.3390/clinpract14030055 |