التفاصيل البيبلوغرافية
| العنوان: |
Macrophage activation syndrome associated with systemic lupus erythematosus treated successfully with the combination of steroid pulse, immunoglobulin and tacrolimus |
| المؤلفون: |
Aoyama-Maeda Natsuki, Horino Taro, Ichii Osamu, Terada Yoshio |
| المصدر: |
Romanian Journal of Internal Medicine, Vol 56, Iss 2, Pp 117-121 (2018) |
| بيانات النشر: |
Sciendo, 2018. |
| سنة النشر: |
2018 |
| المجموعة: |
LCC:Internal medicine |
| مصطلحات موضوعية: |
hemophagocyticlymphohistiocytosis (hlh), intravenous immunoglobulin (ivig), macrophage activation syndrome (mas), systemic lupus erythematosus (sle), tacrolimus (tac), Internal medicine, RC31-1245 |
| الوصف: |
Macrophage activation syndrome (MAS), a variant of secondary hemophagocyticlymphohistiocytosis, is a potentially life-threatening complication of inflammatory and autoimmune diseases. We present a case of MAS as a rare manifestation of systemic lupus erythematosus. Although initial treatment with corticosteroid, with or without cyclosporine A, is justified in patients with MAS, evidence regarding the effectiveness of this treatment protocol remains to be clarified. Our patient was successfully treated with a combination of intravenous immunoglobulin therapy and intravenous methyl predonisolone pulse therapy, which was followed by a course of oral prednisolone and oral tacrolimus. Based on our experience, we propose tacrolimus to provide a more useful adjuvant treatment to corticosteroid therapy than cyclosporine A. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2501-062X |
| Relation: |
https://doaj.org/toc/2501-062X |
| DOI: |
10.1515/rjim-2017-0043 |
| URL الوصول: |
https://doaj.org/article/d66c5d91c5724f469ac62706263b9609 |
| رقم الانضمام: |
edsdoj.66c5d91c5724f469ac62706263b9609 |
| قاعدة البيانات: |
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