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Resting state functional connectivity in the human spinal cord

التفاصيل البيبلوغرافية
العنوان: Resting state functional connectivity in the human spinal cord
المؤلفون: Robert L Barry, Seth A Smith, Adrienne N Dula, John C Gore
المصدر: eLife, Vol 3 (2014)
بيانات النشر: eLife Sciences Publications Ltd, 2014.
سنة النشر: 2014
المجموعة: LCC:Medicine
LCC:Science
LCC:Biology (General)
مصطلحات موضوعية: fMRI, spinal cord, 7 Tesla, resting state, functional connectivity, Medicine, Science, Biology (General), QH301-705.5
الوصف: Functional magnetic resonance imaging using blood oxygenation level dependent (BOLD) contrast is well established as one of the most powerful methods for mapping human brain function. Numerous studies have measured how low-frequency BOLD signal fluctuations from the brain are correlated between voxels in a resting state, and have exploited these signals to infer functional connectivity within specific neural circuits. However, to date there have been no previous substantiated reports of resting state correlations in the spinal cord. In a cohort of healthy volunteers, we observed robust functional connectivity between left and right ventral (motor) horns, and between left and right dorsal (sensory) horns. Our results demonstrate that low-frequency BOLD fluctuations are inherent in the spinal cord as well as the brain, and by analogy to cortical circuits, we hypothesize that these correlations may offer insight into the execution and maintenance of sensory and motor functions both locally and within the cerebrum.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2050-084X
Relation: https://elifesciences.org/articles/02812; https://doaj.org/toc/2050-084X
DOI: 10.7554/eLife.02812
URL الوصول: https://doaj.org/article/d66b45f7d7954bf7a79f1a378e8cab13
رقم الانضمام: edsdoj.66b45f7d7954bf7a79f1a378e8cab13
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:2050084X
DOI:10.7554/eLife.02812