Academic Journal

Venetoclax for an ATRA and ATO resistance acute promyelocytic leukemia patient with TNRC18::RARA fusion gene

التفاصيل البيبلوغرافية
العنوان: Venetoclax for an ATRA and ATO resistance acute promyelocytic leukemia patient with TNRC18::RARA fusion gene
المؤلفون: Weina Li, Haijie Li, Xueyan Chen, Yan Zheng
المصدر: Leukemia Research Reports, Vol 22, Iss , Pp 100482- (2024)
بيانات النشر: Elsevier, 2024.
سنة النشر: 2024
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: Variant acute promyelocytic leukemia, TNRC18::RARA fusion gene, Pulmonary tuberculosis, Multidrug-resistant infection, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Variant acute promyelocytic leukemia (APL) poses diagnostic and therapeutic challenges primarily because of the absence of PML::RARA. This report presents the case of a patient diagnosed with all-trans retinoic acid (ATRA)-resistant APL harboring the TNRC18::RARA fusion gene. After treatment with venetoclax, azacitidine, and ATRA, the patient achieved complete remission. The patient also developed pulmonary tuberculosis and a multidrug-resistant infection, which improved considerably after antituberculosis treatment and carrimycin, respectively.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2213-0489
Relation: http://www.sciencedirect.com/science/article/pii/S2213048924000724; https://doaj.org/toc/2213-0489
DOI: 10.1016/j.lrr.2024.100482
URL الوصول: https://doaj.org/article/6533d999a7324ee89cb0a65083a9f71c
رقم الانضمام: edsdoj.6533d999a7324ee89cb0a65083a9f71c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22130489
DOI:10.1016/j.lrr.2024.100482