التفاصيل البيبلوغرافية
العنوان: |
Venetoclax for an ATRA and ATO resistance acute promyelocytic leukemia patient with TNRC18::RARA fusion gene |
المؤلفون: |
Weina Li, Haijie Li, Xueyan Chen, Yan Zheng |
المصدر: |
Leukemia Research Reports, Vol 22, Iss , Pp 100482- (2024) |
بيانات النشر: |
Elsevier, 2024. |
سنة النشر: |
2024 |
المجموعة: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: |
Variant acute promyelocytic leukemia, TNRC18::RARA fusion gene, Pulmonary tuberculosis, Multidrug-resistant infection, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: |
Variant acute promyelocytic leukemia (APL) poses diagnostic and therapeutic challenges primarily because of the absence of PML::RARA. This report presents the case of a patient diagnosed with all-trans retinoic acid (ATRA)-resistant APL harboring the TNRC18::RARA fusion gene. After treatment with venetoclax, azacitidine, and ATRA, the patient achieved complete remission. The patient also developed pulmonary tuberculosis and a multidrug-resistant infection, which improved considerably after antituberculosis treatment and carrimycin, respectively. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2213-0489 |
Relation: |
http://www.sciencedirect.com/science/article/pii/S2213048924000724; https://doaj.org/toc/2213-0489 |
DOI: |
10.1016/j.lrr.2024.100482 |
URL الوصول: |
https://doaj.org/article/6533d999a7324ee89cb0a65083a9f71c |
رقم الانضمام: |
edsdoj.6533d999a7324ee89cb0a65083a9f71c |
قاعدة البيانات: |
Directory of Open Access Journals |