Academic Journal

List prices and clinical value of anticancer drugs in China, Japan, and South Korea: a retrospective comparative studyResearch in context

التفاصيل البيبلوغرافية
العنوان: List prices and clinical value of anticancer drugs in China, Japan, and South Korea: a retrospective comparative studyResearch in context
المؤلفون: Jay Pan, Xiaolin Wei, Hao Lu, Xueer Wu, Chunyuan Li, Xuelian Hai, Tianjiao Lan, Quanfang Dong, Yili Yang, Mihajlo Jakovljevic, Jing Zhou
المصدر: The Lancet Regional Health. Western Pacific, Vol 47, Iss , Pp 101088- (2024)
بيانات النشر: Elsevier, 2024.
سنة النشر: 2024
المجموعة: LCC:Public aspects of medicine
مصطلحات موضوعية: Anticancer drugs, Prices, Clinical value, China, Japan, South Korea, Public aspects of medicine, RA1-1270
الوصف: Summary: Background: High prices of anticancer drugs have raised concerns due to their financial impact on patients and healthcare systems. This study aimed to assess the initial and latest list prices and clinical value of reimbursed anticancer drugs in China, Japan, and South Korea. Methods: We identified anticancer drugs newly approved by the National Medical Products Administration of China from January 2012 to June 2022, and by the Pharmaceuticals and Medical Devices Agency of Japan and the Ministry of Food and Drug Safety of South Korea up until June 2022. We compared initial and latest treatment prices between countries and assessed clinical value using patients’ survival, quality of life (QoL), and European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS). We calculated Spearman rank correlation coefficients of treatment prices with clinical value for individual countries and employed regression analyses to investigate whether the relationship between prices and clinical value was modified by the country setting. Findings: Our cohort included 91 anticancer drug indications, with 60 listed for reimbursement in China, 91 in Japan, and 87 in South Korea. Median treatment prices were highest in Japan, followed by South Korea, and lowest in China, both for initial prices (US$64082 vs. US$45529 vs. US$19144, p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2666-6065
Relation: http://www.sciencedirect.com/science/article/pii/S2666606524000828; https://doaj.org/toc/2666-6065
DOI: 10.1016/j.lanwpc.2024.101088
URL الوصول: https://doaj.org/article/64a9814305a64c4e8ae4427646f3118d
رقم الانضمام: edsdoj.64a9814305a64c4e8ae4427646f3118d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:26666065
DOI:10.1016/j.lanwpc.2024.101088