Academic Journal
Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysis.
| العنوان: | Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysis. |
|---|---|
| المؤلفون: | Steven C Moore, Alpa V Patel, Charles E Matthews, Amy Berrington de Gonzalez, Yikyung Park, Hormuzd A Katki, Martha S Linet, Elisabete Weiderpass, Kala Visvanathan, Kathy J Helzlsouer, Michael Thun, Susan M Gapstur, Patricia Hartge, I-Min Lee |
| المصدر: | PLoS Medicine, Vol 9, Iss 11, p e1001335 (2012) |
| بيانات النشر: | Public Library of Science (PLoS), 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | Medicine |
| الوصف: | BackgroundLeisure time physical activity reduces the risk of premature mortality, but the years of life expectancy gained at different levels remains unclear. Our objective was to determine the years of life gained after age 40 associated with various levels of physical activity, both overall and according to body mass index (BMI) groups, in a large pooled analysis.Methods and findingsWe examined the association of leisure time physical activity with mortality during follow-up in pooled data from six prospective cohort studies in the National Cancer Institute Cohort Consortium, comprising 654,827 individuals, 21-90 y of age. Physical activity was categorized by metabolic equivalent hours per week (MET-h/wk). Life expectancies and years of life gained/lost were calculated using direct adjusted survival curves (for participants 40+ years of age), with 95% confidence intervals (CIs) derived by bootstrap. The study includes a median 10 y of follow-up and 82,465 deaths. A physical activity level of 0.1-3.74 MET-h/wk, equivalent to brisk walking for up to 75 min/wk, was associated with a gain of 1.8 (95% CI: 1.6-2.0) y in life expectancy relative to no leisure time activity (0 MET-h/wk). Higher levels of physical activity were associated with greater gains in life expectancy, with a gain of 4.5 (95% CI: 4.3-4.7) y at the highest level (22.5+ MET-h/wk, equivalent to brisk walking for 450+ min/wk). Substantial gains were also observed in each BMI group. In joint analyses, being active (7.5+ MET-h/wk) and normal weight (BMI 18.5-24.9) was associated with a gain of 7.2 (95% CI: 6.5-7.9) y of life compared to being inactive (0 MET-h/wk) and obese (BMI 35.0+). A limitation was that physical activity and BMI were ascertained by self report.ConclusionsMore leisure time physical activity was associated with longer life expectancy across a range of activity levels and BMI groups. Please see later in the article for the Editors' Summary. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1549-1277 1549-1676 |
| Relation: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23139642/?tool=EBI; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676 |
| DOI: | 10.1371/journal.pmed.1001335 |
| URL الوصول: | https://doaj.org/article/64a60794428f45e6bc368e31212ef88f |
| رقم الانضمام: | edsdoj.64a60794428f45e6bc368e31212ef88f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15491277 15491676 |
|---|---|
| DOI: | 10.1371/journal.pmed.1001335 |