Academic Journal
Metal Release and Cell Viability of 316L Stainless Steel Sputter-Coated with N-Doped a-C:H Coatings
| العنوان: | Metal Release and Cell Viability of 316L Stainless Steel Sputter-Coated with N-Doped a-C:H Coatings |
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| المؤلفون: | António Fróis, João Ricardo Marques, Luís Santos, Marco Peres, Katharina Lorenz, Cristina Santos Louro, Ana Cristina Santos |
| المصدر: | Applied Sciences, Vol 14, Iss 22, p 10500 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Technology LCC:Engineering (General). Civil engineering (General) LCC:Biology (General) LCC:Physics LCC:Chemistry |
| مصطلحات موضوعية: | cytotoxicity, corrosion, DLC coatings, hydrogenated amorphous carbon (a-C:H), metal release, nitrogen doping, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999 |
| الوصف: | Hydrogenated amorphous carbon (a-C:H) has been considered a promising biocompatible coating to protect metallic alloys against corrosion for medical applications, namely orthodontics. However, there is still no optimal solution for this biomedical field; hence, the investigation remains open. In this work, the effect of a nonmetallic doping element (N) on sputter-deposited a-C:H coatings was studied concerning both salivary corrosion and cytotoxicity behavior. After a 30-day corrosion test in an acidic modified Fusayama-Meyer artificial saliva, metal release from both coated and uncoated 316L stainless steel (SS) substrates was quantified. Tests on the corrosion extracts were then performed by using monocultures of macrophages and fibroblasts, and their coculture; and cell viability was evaluated via the MTT test. Results show an overall inhibition of the SS corrosion, which enhanced the in vitro biocompatibility with a minimal effect on the coatings’ microstructure. Among all the coatings tested, the undoped a-C:H coating performed the best, whereas an increase in N doping led to poorer protection against metal dissolution and a subsequent slightly lower biocompatibility. The findings corroborate that selecting the nonmetallic element N for doping C-based coatings is not a good choice for this biomedical field, even at low contents up to 10 at.%. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2076-3417 |
| Relation: | https://www.mdpi.com/2076-3417/14/22/10500; https://doaj.org/toc/2076-3417 |
| DOI: | 10.3390/app142210500 |
| URL الوصول: | https://doaj.org/article/63dd08c9de114996ad4b0a4ff8339d98 |
| رقم الانضمام: | edsdoj.63dd08c9de114996ad4b0a4ff8339d98 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20763417 |
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| DOI: | 10.3390/app142210500 |