Academic Journal
Retrospective cohort study of the risk of impaired glucose tolerance among shift workers
العنوان: | Retrospective cohort study of the risk of impaired glucose tolerance among shift workers |
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المؤلفون: | Ichiro Oyama, Tomohide Kubo, Yoshihisa Fujino, Koji Kadowaki, Masamizu Kunimoto, Kiyoyumi Shirane, Hidetoshi Tabata, Ken Sabanai, Takehiro Nakamura, Shinya Matsuda |
المصدر: | Scandinavian Journal of Work, Environment & Health, Vol 38, Iss 4, Pp 337-342 (2012) |
بيانات النشر: | Nordic Association of Occupational Safety and Health (NOROSH), 2012. |
سنة النشر: | 2012 |
المجموعة: | LCC:Public aspects of medicine |
مصطلحات موضوعية: | retrospective cohort study, impaired glucose tolerance, glucose, glucose metabolism disorder, historical cohort study, cohort study, japan, shift work, shift worker, retrospective study, work schedule tolerance, Public aspects of medicine, RA1-1270 |
الوصف: | OBJECTIVES: The aim of this study was to investigate the effect of shift working on the risk of developing impaired glucose tolerance (IGT). METHODS: This study comprised 6413 male employees (5608 daytime workers, 512 3-shift workers and 293 2-shift workers) whose work schedules remained constant during the follow-up period (mean follow-up period 9.9 years). IGT was defined as Hemoglobin A1c ≥5.9%. The Cox proportional hazards model was used to estimate the risk of developing IGT, after making adjustments for age, smoking, alcohol consumption, leisure-time physical activity, body mass index (BMI) and Hemoglobin A1c (HbA1c) at baseline. Analysis was additionally performed for a sub-cohort of 1625 workers with BMI of 20.0–25.0 kg/m^2 that did not change by >2.0 kg/m^2 during the follow up period. RESULTS: The risk of developing IGT was significantly elevated among both 3-shift workers [hazard ratio (HR) 1.78, 95% confidence interval (95% CI) 1.49– 2.14] and 2-shift workers (HR 2.62, 95% CI 2.17–3.17). Significant elevations of the risk were still observed at the additional analysis on the sub-cohort (3-shift work: HR 3.55, 95% CI 2.02–6.25; 2-shift work: HR 4.86, 95% CI 2.62–9.01). CONCLUSIONS: Both 2- and 3-shift workers were associated with a high risk factor of developing IGT compared to day workers. Moreover, 2-shift workers had a higher risk than 3-shift workers. The risk was observed even among workers whose body mass remained within the normal range. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0355-3140 1795-990X |
Relation: | https://www.sjweh.fi/show_abstract.php?abstract_id=3297; https://doaj.org/toc/0355-3140; https://doaj.org/toc/1795-990X |
DOI: | 10.5271/sjweh.3297 |
URL الوصول: | https://doaj.org/article/635f934ffd1646848eecfdef0d5ae9f0 |
رقم الانضمام: | edsdoj.635f934ffd1646848eecfdef0d5ae9f0 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 03553140 1795990X |
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DOI: | 10.5271/sjweh.3297 |