Academic Journal

Interpretation of the effects of rumen acidosis on the gut microbiota and serum metabolites in calves based on 16S rDNA sequencing and non-target metabolomics

التفاصيل البيبلوغرافية
العنوان: Interpretation of the effects of rumen acidosis on the gut microbiota and serum metabolites in calves based on 16S rDNA sequencing and non-target metabolomics
المؤلفون: Fanlin Wu, Peng Ji, Haochi Yang, Xiaopeng Zhu, Xiaohu Wu
المصدر: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
بيانات النشر: Frontiers Media S.A., 2024.
سنة النشر: 2024
المجموعة: LCC:Microbiology
مصطلحات موضوعية: calves, rumen acidosis, gut microbiota, serum metabolites, correlation analysis, Microbiology, QR1-502
الوصف: IntroductionRumen acidosis is one of the most common diseases in beef cattle. It severely affects the normal development of calves and poses a significant threat to the farming industry. However, the influence of rumen acidosis on the gut microbiota and serum metabolites of calves is currently unclear.ObjectiveThe aim of this study is to investigate the changes in the gut microbiota and serum metabolites in calves after rumen acidosis and analyse the correlation.MethodsEight calves were selected as the rumen acidosis group, and eight health calves were selected as the healthy group. The faecal gut microbiota and serum metabolites of calves were detected respectively using 16S rDNA high-throughput sequencing and non-target metabolomics. The correlation between gut microbiota and serum metabolites was analyzed by Spearman correlation analysis.ResultsDifferential analysis of the diversity and composition of gut microbiota between eight male healthy (Health) and eight male rumen acidosis (Disease) calves revealed that rumen acidosis increased the abundance of the gut microbiota in calves. At the phylum level, compared to the Healthy group, the relative abundance of Proteobacteria in the Disease group significantly decreased (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2235-2988
Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2024.1427763/full; https://doaj.org/toc/2235-2988
DOI: 10.3389/fcimb.2024.1427763
URL الوصول: https://doaj.org/article/6325571901844e7886ada8bc1dea796f
رقم الانضمام: edsdoj.6325571901844e7886ada8bc1dea796f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22352988
DOI:10.3389/fcimb.2024.1427763