التفاصيل البيبلوغرافية
| العنوان: |
The expression of DNAJB9 in normal human astrocytes is more sensitive to nanographene oxide than in glioblastoma cells |
| المؤلفون: |
Minchenko Oleksandr, Kulish Yuliia V., Viletska Yuliia M., Khita Olena O., Rudnytska Olha V., Kozynkevych Halyna E., Minchenko Dmytro O. |
| المصدر: |
Endocrine Regulations, Vol 58, Iss 1 (2024) |
| بيانات النشر: |
Sciendo, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: |
nanographene oxide, dnajb9, ddit3, edem1, idh2, mrna expression, geno-toxicity, ern1 knockdown, normal human astrocytes, glioblastoma cells, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: |
Objective. Nanographene oxide (nGO) nanoparticles (NPs) have unique properties and are widely used in various fields, including biomedicine. These NPs, however, also exhibit toxic effects and therefore, the understanding of the molecular mechanism of nGO toxicity is very important mainly for the nanomedicine, especially the cancer therapy. This study aimed to examine the impact of nGO NPs on the expression of genes associated with endoplasmic reticulum (ER) stress, proliferation, and cancerogenesis in both normal human astrocytes and U87MG glioblastoma cells. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1336-0329 |
| Relation: |
https://doaj.org/toc/1336-0329 |
| DOI: |
10.2478/enr-2024-0029 |
| URL الوصول: |
https://doaj.org/article/6299f828db9e43e8b2edc77ee876dee1 |
| رقم الانضمام: |
edsdoj.6299f828db9e43e8b2edc77ee876dee1 |
| قاعدة البيانات: |
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