Academic Journal

Economic and clinical burden from carbapenem-resistant bacterial infections and factors contributing: a retrospective study using electronic medical records in Japan

التفاصيل البيبلوغرافية
العنوان: Economic and clinical burden from carbapenem-resistant bacterial infections and factors contributing: a retrospective study using electronic medical records in Japan
المؤلفون: Shinobu Imai, Norihiko Inoue, Hideaki Nagai
المصدر: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
بيانات النشر: BMC, 2022.
سنة النشر: 2022
المجموعة: LCC:Infectious and parasitic diseases
مصطلحات موضوعية: Carbapenem resistance, Carbapenem-susceptible infection, Length of hospital stay, Hospitalization cost, Electronic medical records, Infectious and parasitic diseases, RC109-216
الوصف: Abstract Background Antimicrobial resistance is a major threat to global health and the world economy. The economic burden of carbapenem-resistant infections has not previously been evaluated. We aimed to compare the potential economic burden and clinical outcomes between carbapenem-resistant infections and carbapenem-susceptible infections in Japan. Methods We conducted a retrospective cohort study using electronic medical records. Patients aged 15 years or older and with the diagnosis of pneumonia, urinary tract infection, biliary infection, and sepsis were included. Multivariable regression models with random effects were used to estimate the impact of carbapenem resistance on cost, length of hospital stay, and in-hospital mortality. Results Among the 9,517 patients, 86 (0.9%) had carbapenem-resistant (CR) infections. Compared to carbapenem-susceptible (CS) infections, the patients with the CR infections were significantly more likely to receive mechanical ventilation (37.2 vs. 21.2%, P-value = 0.003), antibiotics (88.4 vs. 63.0%, P-value
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2334
Relation: https://doaj.org/toc/1471-2334
DOI: 10.1186/s12879-022-07548-3
URL الوصول: https://doaj.org/article/6106d85e8f59414babe26d2d3f3403f6
رقم الانضمام: edsdoj.6106d85e8f59414babe26d2d3f3403f6
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712334
DOI:10.1186/s12879-022-07548-3