التفاصيل البيبلوغرافية
| العنوان: |
Long‐term follow‐up of intradetrusor botulinum toxin utilisation: A comparison of patients with multiple sclerosis and idiopathic overactive bladder |
| المؤلفون: |
William Chui, Joshua Kealey, Henry H. Yao, Garson Chan, Alvaro Bazo, Richard Parkinson, Helen E. O'Connell, Johan Gani |
| المصدر: |
BJUI Compass, Vol 6, Iss 1, Pp n/a-n/a (2025) |
| بيانات النشر: |
Wiley, 2025. |
| سنة النشر: |
2025 |
| المجموعة: |
LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: |
bladder, detrusor, efficacy, incontinence, multiple sclerosis, neurogenic, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: |
Abstract Objectives To assess long‐term outcomes (up to 10 cycles) of repeated intradetrusor botulinum toxin (BoNT) utilisation in multiple sclerosis (MS) and idiopathic overactive bladder (OAB). Materials and Methods This is a retrospective, international, multi‐centre, observational cohort study of patients diagnosed with MS and neurogenic OAB and treated with intradetrusor BoNT between January 2005 and January 2020 (just prior to COVID‐19 interruption). Dose, efficacy, duration of effect, International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ‐OAB) and International Consultation on Incontinence Questionnaire Urinary Incontinence (ICIQ‐UI) measures and complication rates were recorded. Comparisons were made to those with idiopathic OAB. Results Seven hundred and ninety‐two patients received intradetrusor BoNT treatment (104 had MS with neurogenic OAB and 688 had idiopathic OAB). Patients with MS were more likely to receive higher doses of BoNT in all cycles. Self‐reported efficacy ranged from 85.7 to 100% (MS) and 87.2 to 100% (idiopathic) with MS patients reporting increased efficacy in cycles 1–3 comparatively (p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2688-4526 |
| Relation: |
https://doaj.org/toc/2688-4526 |
| DOI: |
10.1002/bco2.479 |
| URL الوصول: |
https://doaj.org/article/5fcfcde92e60449fa80013fca83527a5 |
| رقم الانضمام: |
edsdoj.5fcfcde92e60449fa80013fca83527a5 |
| قاعدة البيانات: |
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