Academic Journal
A challenging case of Francisella Tularensis: teenager’s massive lymphoadenopathy caused by an uncommon infectious disease.
| العنوان: | A challenging case of Francisella Tularensis: teenager’s massive lymphoadenopathy caused by an uncommon infectious disease. |
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| المؤلفون: | G. Castellana, M. Ciuffreda, E. Pisello, U.W. Basso, J. Silvestri, M. Caimmi, A. Pennacchi, D. Galante, C. Piangatelli |
| المصدر: | Pediatric Anesthesia and Critical Care Journal (PACCJ), Vol 10, Iss 1, Pp 32-36 (2022) |
| بيانات النشر: | Pediatric Anesthesia and Critical Care Journal, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Pediatrics LCC:Anesthesiology |
| مصطلحات موضوعية: | lymphadenopathy, tularaemia, francisella tularensis, head and neck infection, granulomatous disease, pediat- ric infection, tonsillar hypertrophy, Pediatrics, RJ1-570, Anesthesiology, RD78.3-87.3 |
| الوصف: | Tularemia is a potentially fatal, multisystemic infectious disease of humans and some animals caused by Fran- cisella Tularensis bacteria. Up to six forms of clinical manifestations of tularemia have been identified, ulcer- oglandular tularemia being the most common form. Up- per airway manifestations of tularemia include tonsillar hypertrophy and pharyngitis, accompanied by cervical lymphadenopathies. Anatomical alterations of the cervi- cal district represent an additional risk in airways man- agement. Between 2016 and 2019, only three cases of tu- laremia have been described in Italy, but some authors consider Tularemia underreported, especially in Europe. We describe a case of a 17-year-old boy who presented to our clinic with massive cervical left lymphadenopathy and enlargement of the ipsilateral palatine tonsil associ- ated with fever. The symptoms persisted after antibiotic and corticosteroid treatment. To exclude a lymphoprolif- erative disease, a full body CT scan with contrast was performed, showing multiple cervical bilateral lymphadenopathies, especially on the left side and hyper- trophy of the left palatine tonsil and splenomegaly. The biopsy of the left tonsil, performed under general anes- thesia, demonstrated a granulomatous inflammation. A more accurate reconstruction of the patient history re- vealed domestic presence of rabbits. Therefore, serologic and molecular tests for F. Tularensis were performed, with positive results. Proper antibiotic treatment was ad- ministered with gradual and complete symptoms regres- sion. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2281-8421 |
| Relation: | http://www.anestesiarianimazione.com/PACCJ%202022/Francisella%20Tularensis.pdf; https://doaj.org/toc/2281-8421 |
| DOI: | 10.14587/paccj.2022.5 |
| URL الوصول: | https://doaj.org/article/5ef4b16394b54eb080083840b5bfde9f |
| رقم الانضمام: | edsdoj.5ef4b16394b54eb080083840b5bfde9f |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 22818421 |
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| DOI: | 10.14587/paccj.2022.5 |