التفاصيل البيبلوغرافية
| العنوان: |
Differential dynamics of hepatic protein expressions with long-term cultivated hepatitis C virus infection |
| المؤلفون: |
Peiju Tsai, Tze-Yu Lin, Shiang-Lin Cheng, Hung-Yu Sun, Sung-Fang Chen, Kung-Chia Young |
| المصدر: |
Journal of Microbiology, Immunology and Infection, Vol 53, Iss 5, Pp 715-723 (2020) |
| بيانات النشر: |
Elsevier, 2020. |
| سنة النشر: |
2020 |
| المجموعة: |
LCC:Microbiology |
| مصطلحات موضوعية: |
Acute and chronic infections, Comparative proteomics, Functional pathway clustering, Hepatitis C virus, Intracellular trafficking, Microbiology, QR1-502 |
| الوصف: |
Background: The liver maintains blood chemical homeostasis by active uptake and secretion through endocytosis, exocytosis, and intracellular trafficking between the plasma and intracellular membranes. Hepatitis C virus (HCV) infection affects the host membrane architecture and might thus impair the regulation of the cellular transportation machinery. Additionally, the hepatic expressions of differential protein dynamics with long-term HCV infection remain fully recover. Methods: In this study, comparative proteomic analysis was performed in HCV-infected and mock-control Huh7 cells according to the viral dynamics of exponential, plateau, declined, and silencing phases at the acute stage, and the chronic stage. The proteins with |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1684-1182 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1684118218302706; https://doaj.org/toc/1684-1182 |
| DOI: |
10.1016/j.jmii.2019.01.003 |
| URL الوصول: |
https://doaj.org/article/5d893808017e40649a29d787385cbd60 |
| رقم الانضمام: |
edsdoj.5d893808017e40649a29d787385cbd60 |
| قاعدة البيانات: |
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