Academic Journal
Association between alcohol intake and death from cardiovascular diseases and its subtypes stratified by dyslipidemia in Japanese men: 20-years follow-up of NIPPON DATA90
| العنوان: | Association between alcohol intake and death from cardiovascular diseases and its subtypes stratified by dyslipidemia in Japanese men: 20-years follow-up of NIPPON DATA90 |
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| المؤلفون: | Takumi Hirata, Aya Hirata, Sayuki Torii, Naoyuki Takashima, Aya Kadota, Sohel Reza Choudhury, Akira Okayama, Katsuyuki Miura, Tomonori Okamura, NIPPON DATA90 Study Group |
| المصدر: | Environmental Health and Preventive Medicine, Vol 29, Pp 61-61 (2024) |
| بيانات النشر: | Komiyama Printing Co. Ltd, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Public aspects of medicine |
| مصطلحات موضوعية: | alcohol intake, cardiovascular disease, cohort study, dyslipidemia, Public aspects of medicine, RA1-1270 |
| الوصف: | Background: The association between alcohol consumption and atherosclerotic cardiovascular disease (ASCVD) was controversial, and no previous studies have shown the impact of dyslipidemia on the association. We aimed to clarify the association between alcohol consumption and death from cardiovascular disease (CVD) and its subtypes and the impact of dyslipidemia on the association. Methods: We conducted a 20-year cohort study to clarify the association between alcohol intake and death from CVD and its subtypes in 2,909 Japanese men. We estimated the hazard ratio (HR) and 95% confidence intervals (CIs) for current drinkers with non-drinkers as the reference, after adjusting for potential confounders using Cox proportional hazards models. We also investigated the association between alcohol consumption and ASCVD or CVD death stratified by the presence or absence of dyslipidemia. Results: During 50,782 person-years of follow-up period, 223 participants died from total CVD, 110 participants died from ASCVD, and 25 participants died from cerebral hemorrhage. Current drinkers with 1 gou/day were significantly associated with lower risk of ASCVD (HR: 0.60, 95%CI: 0.37–0.98), which is more apparent in those without dyslipidemia, and current drinkers with ≥3 gou/day were significantly associated with higher risk of cerebral hemorrhage (HR: 4.13, 95%CI: 1.12–15.19). Conclusions: Small amounts of alcohol drinking were associated with lower risk of ASCVD in Japanese men, especially those without dyslipidemia. Meanwhile, excessive alcohol drinking was associated with higher risk of cerebral hemorrhage. Our findings suggest that it is important for current Japanese drinkers to reduce alcohol consumption for preventing ASCVD or cerebral hemorrhage. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1342-078X 1347-4715 |
| Relation: | https://www.jstage.jst.go.jp/article/ehpm/29/0/29_24-00164/_html/-char/en; https://doaj.org/toc/1342-078X; https://doaj.org/toc/1347-4715 |
| DOI: | 10.1265/ehpm.24-00164 |
| URL الوصول: | https://doaj.org/article/5d70037e063841c1bea600de6f84dbd6 |
| رقم الانضمام: | edsdoj.5d70037e063841c1bea600de6f84dbd6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1342078X 13474715 |
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| DOI: | 10.1265/ehpm.24-00164 |