Academic Journal
Novel Polymorphisms of Adrenergic, Alpha-1B-, Receptor and Peroxisome Proliferator-activated Receptor Gamma, Coactivator 1 Beta Genes and Their Association with Egg Production Traits in Local Chinese Dagu Hens
| العنوان: | Novel Polymorphisms of Adrenergic, Alpha-1B-, Receptor and Peroxisome Proliferator-activated Receptor Gamma, Coactivator 1 Beta Genes and Their Association with Egg Production Traits in Local Chinese Dagu Hens |
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| المؤلفون: | F. Mu, Y. Jing, N. Qin, H. Y. Zhu, D. H. Liu, S. G. Yuan, R. F. Xu |
| المصدر: | Asian-Australasian Journal of Animal Sciences, Vol 29, Iss 9, Pp 1256-1264 (2016) |
| بيانات النشر: | Asian-Australasian Association of Animal Production Societies, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Animal culture LCC:Animal biochemistry |
| مصطلحات موضوعية: | Polymorphisms, Chinese Dagu Hens, Egg Production Traits, Animal culture, SF1-1100, Animal biochemistry, QP501-801 |
| الوصف: | Adrenergic, alpha-1B-, receptor (ADRA1B) and peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B) genes are involved in regulation of hen ovarian development. In this study, these two genes were investigated as possible molecular markers associated with hen-housed egg production, egg weight (EW) and body weight in Chinese Dagu hens. Samples were analyzed using the polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique, followed by sequencing analysis. Two novel single nucleotide polymorphisms (SNPs) were identified within the candidate genes. Among them, an A/G transition at base position 1915 in exon 2 of ADRA1B gene and a T/C mutation at base position 6146 in the 3′-untranslated region (UTR) of PPARGC1B gene were found to be polymorphic and named SNP A1915G and T6146C, respectively. The SNP A1915G (ADRA1B) leads to a non-synonymous substitution (aspartic acid 489-to-glycine). The 360 birds from the Dagu population were divided into genotypes AA and AG, allele A was found to be present at a higher frequency. Furthermore, the AG genotype correlated with significantly higher hen-housed egg production (HHEP) at 30, 43, 57, and 66 wks of age and with a higher EW at 30 and 43 wks (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1011-2367 1976-5517 |
| Relation: | http://www.ajas.info/upload/pdf/ajas-29-9-1256.pdf; https://doaj.org/toc/1011-2367; https://doaj.org/toc/1976-5517 |
| DOI: | 10.5713/ajas.15.0794 |
| URL الوصول: | https://doaj.org/article/5d07888876094eb88013c606640ad77b |
| رقم الانضمام: | edsdoj.5d07888876094eb88013c606640ad77b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 10112367 19765517 |
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| DOI: | 10.5713/ajas.15.0794 |