التفاصيل البيبلوغرافية
| العنوان: |
Enhanced Effect of Patient Room Disinfection Against Carbapenem-Resistant Enterobacter cloacae and Methicillin-Resistant Staphylococcus aureus Using UV-C Irradiation in Conjunction with UV-C Containment Unit |
| المؤلفون: |
Shiori Kitaya, Kentarou Takei, Yoshitomo Honda, Risako Kakuta, Hajime Kanamori |
| المصدر: |
Antibiotics, Vol 13, Iss 12, p 1115 (2024) |
| بيانات النشر: |
MDPI AG, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Therapeutics. Pharmacology |
| مصطلحات موضوعية: |
ultraviolet-C, UV-C containment unit, environmental transmission, carbapenem-resistant Enterobacter cloacae, methicillin-resistant Staphylococcus aureus, Therapeutics. Pharmacology, RM1-950 |
| الوصف: |
Background/Objectives: In environments with high-frequency contact surfaces, drug-resistant bacteria, such as carbapenem-resistant Enterobacterales and methicillin-resistant Staphylococcus aureus (MRSA), can survive for extended periods, contributing to healthcare-associated infections. Ultraviolet (UV)-C irradiation often fails to adequately disinfect shadowed areas, leading to a persistent contamination risk. We evaluated the effectiveness of using a UV-C containment unit (UVCCU) in conjunction with UV-C irradiation to improve the sterilization effects on both direct and indirect surfaces, including shadowed areas, and to assess the leakage of UV radiation to the surroundings. Methods: In a model patient room, agar media inoculated with carbapenem-resistant Enterobacter cloacae and MRSA were placed at multiple locations on direct and indirect surfaces around the bed. We used the UV-C irradiation system, UVDI-360, to irradiate the bedroom-environment surfaces with and without a UVCCU. The reduction in bacterial colony counts with and without the UVCCU was measured by counting colony-forming units and calculating the log reduction values, and the UV radiation leakage outside the UVCCU was measured. Results: The use of the UVCCU led to a significant reduction in MRSA colony counts, even in shadowed areas that had previously been inadequately disinfected (with the UVCCU: 2.7 [2.7–2.8]; without the UVCCU: 0.6 [0.5–0.7]; p < 0.01). Additionally, the use of the UVCCU kept the UV radiation leakage to the surrounding environment within regulated limits. Conclusions: These findings suggest that a UVCCU can enhance the disinfection efficacy for multidrug-resistant organisms on healthcare environmental surfaces. The portability and ease of use of the UVCCU indicate its promise as an auxiliary device for UV-C disinfection in healthcare settings. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2079-6382 |
| Relation: |
https://www.mdpi.com/2079-6382/13/12/1115; https://doaj.org/toc/2079-6382 |
| DOI: |
10.3390/antibiotics13121115 |
| URL الوصول: |
https://doaj.org/article/5c4d15f7312e4271b89c5d4f14edab40 |
| رقم الانضمام: |
edsdoj.5c4d15f7312e4271b89c5d4f14edab40 |
| قاعدة البيانات: |
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