Academic Journal

Electrochemical Behaviour and Direct Cell Viability Analysis of Hybrid Implants Made of Ti-6Al-4V Lattices Infiltrated with a Bioabsorbable Zn-Based Alloy

التفاصيل البيبلوغرافية
العنوان: Electrochemical Behaviour and Direct Cell Viability Analysis of Hybrid Implants Made of Ti-6Al-4V Lattices Infiltrated with a Bioabsorbable Zn-Based Alloy
المؤلفون: Noa Gabay Bass, Galit Katarivas Levy, Tomer Ron, Razi Vago, Jeremy Goldman, Amnon Shirizly, Eli Aghion
المصدر: Metals, Vol 12, Iss 10, p 1735 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Mining engineering. Metallurgy
مصطلحات موضوعية: osseointegration, additive manufacturing, SLM, lattice, Ti–6Al–4V, biodegradable zinc, Mining engineering. Metallurgy, TN1-997
الوصف: Biodegradable metals are being developed for biomedical implants or components of implants. Biodegradable zinc-based materials, in particular, have been shown to promote bone regeneration in orthopaedic applications. Here, we investigated the potential of a hybrid Ti-Zn system, comprising a Ti-6Al-4V biostable lattice produced by additive manufacturing (AM) infiltrated by a bioabsorbable Zn-2%Fe alloy, to serve as an osseointegrated implant for dental and orthopaedic applications. The osseointegration of implants can be enhanced by a porous implant structure that facilitates bone ingrowth to achieve superior bonding between the bone tissue and the implant. The hybrid material was evaluated in terms of microstructure and localized chemical composition using scanning and transmission electron microscopy with special attention to the interface between the Ti-based lattice and the biodegradable alloy. The electrochemical behaviour of the Ti-Zn system was analysed in a simulated physiological environment in terms of open circuit potential test and cyclic potentiodynamic polarization. Cytotoxicity was evaluated using direct cell viability tests. The results demonstrate desirable properties of the hybrid Ti-Zn system as a non-cytotoxic material with an acceptable corrosion rate.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2075-4701
Relation: https://www.mdpi.com/2075-4701/12/10/1735; https://doaj.org/toc/2075-4701
DOI: 10.3390/met12101735
URL الوصول: https://doaj.org/article/d5afe34fde3b48faaf709fd898d7ccf3
رقم الانضمام: edsdoj.5afe34fde3b48faaf709fd898d7ccf3
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20754701
DOI:10.3390/met12101735