Academic Journal
Enoxaparin-induced hepatotoxicity: clinical cases and literature review
| العنوان: | Enoxaparin-induced hepatotoxicity: clinical cases and literature review |
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| المؤلفون: | Yu. N. Krovko, A. V. Shmigelskiy, A. D. Аkhmedov, A. A. Shulgina, V. A. Lukshin, D. Yu. Usachev |
| المصدر: | Вестник анестезиологии и реаниматологии, Vol 18, Iss 1, Pp 84-92 (2021) |
| بيانات النشر: | New Terra Publishing House, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medical emergencies. Critical care. Intensive care. First aid |
| مصطلحات موضوعية: | drug-induced liver injury, enoxaparin, low molecular weight heparins, hepatotoxicity, deep vein thrombosis, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9 |
| الوصف: | Low molecular weight heparins, in particular enoxaparin, have a wide range of applications, including prevention and treatment of deep vein thrombosis. The most common adverse effects of these drugs are bleeding and thrombocytopenia, but a clinician should be aware of another less common but not less important adverse effect such as an elevated transaminase level. In 2019, we observed two cases of enoxaparin-induced hepatotoxicity. In the first one, enoxaparin 0.4 ml subcutaneously twice a day was prescribed to a 40-year-old woman as a bridge therapy to discontinue warfarin before elective surgery. In the second case, a 27-year-old man received enoxaparin 0.4 ml subcutaneously twice a day for the prevention of deep vein thrombosis. The elevation of transaminase level for more than 3 times above the norm was noted in both patients which required discontinuation of the drug. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 2078-5658 2541-8653 |
| Relation: | https://www.vair-journal.com/jour/article/view/501; https://doaj.org/toc/2078-5658; https://doaj.org/toc/2541-8653 |
| DOI: | 10.21292/2078-5658-2021-18-1-84-92 |
| URL الوصول: | https://doaj.org/article/5aefd211bbb24068b35f1b23a9f6bbd0 |
| رقم الانضمام: | edsdoj.5aefd211bbb24068b35f1b23a9f6bbd0 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 20785658 25418653 |
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| DOI: | 10.21292/2078-5658-2021-18-1-84-92 |