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Juvenile unilesional folliculotropic mycosis fungoides: Two siblings with HLA-DRB1*04 and HLA-DQB1*03 alleles

التفاصيل البيبلوغرافية
العنوان: Juvenile unilesional folliculotropic mycosis fungoides: Two siblings with HLA-DRB1*04 and HLA-DQB1*03 alleles
المؤلفون: Hatice Şanlı, İncilay Kalay Yıldızhan, Bengü Nisa Akay, Canan Arı, Aylin Okçu Heper
المصدر: Turkderm Turkish Archives of Dermatology and Venereology, Vol 56, Iss 2, Pp 76-79 (2022)
بيانات النشر: Galenos Publishing House, 2022.
سنة النشر: 2022
المجموعة: LCC:Dermatology
LCC:Diseases of the genitourinary system. Urology
مصطلحات موضوعية: mycosis fungoides, juvenile, familial, unilesional, folliculotropic, hla alleles, Dermatology, RL1-803, Diseases of the genitourinary system. Urology, RC870-923
الوصف: The pathogenesis of mycosis fungoides (MF) is poorly understood, and an immunogenetic mechanism has been suggested to play a role. Human leukocyte antigen (HLA) class II alleles DRB1*11 and DQB1*03 were found to be significantly increased for patients with sporadic and/ or familial MF. The juvenile-onset familial MF is extremely rare. Herein, we report two siblings diagnosed with folliculotropic MF, both exhibiting similar morphology of a unilesional presentation on the flexural region of the arms. Both were positive for HLA-DRB1*04 and HLA-DQB1*03 alleles. The HLA-DQB1*03 allele has been described in familial MF in the literature recently, whereas “HLA-DRB1*04” allele has not been reported previously in familial MF cases.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Turkish
تدمد: 2651-5164
Relation: https://journal.turkderm.org.tr/jvi.aspx?pdir=turkderm&plng=eng&un=TURKDERM-89083&look4=; https://doaj.org/toc/2651-5164
DOI: 10.4274/turkderm.galenos.2022.89083
URL الوصول: https://doaj.org/article/c58fe53d23474fccad7081d33eab6bd2
رقم الانضمام: edsdoj.58fe53d23474fccad7081d33eab6bd2
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:26515164
DOI:10.4274/turkderm.galenos.2022.89083