Academic Journal
Comparison of two doses of hypobaric bupivacaine in unilateral spinal anesthesia for hip fracture surgery: 5 mg versus 7.5 mg
| العنوان: | Comparison of two doses of hypobaric bupivacaine in unilateral spinal anesthesia for hip fracture surgery: 5 mg versus 7.5 mg |
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| المؤلفون: | Mohamed Kahloul, Mohamed Said Nakhli, Amine Chouchene, Nidhal Chebbi, Salah Mhamdi, Walid Naija |
| المصدر: | The Pan African Medical Journal, Vol 28, Iss 108 (2017) |
| بيانات النشر: | The Pan African Medical Journal, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | unilateral spinal anesthesia, hypobaric bupivacaine, low doses, hip fracture, Medicine |
| الوصف: | INTRODUCTION: hip fracture is a frequent and severe disease. Its prognosis depends on the perioperative hemodynamic stability which can be preserved by the unilateral spinal anesthesia especially with low doses of local anesthetics. This study aims to compare the efficacy and hemodynamic stability of two doses of hypobaric bupivacaine (7.5 mg vs 5 mg) in unilateral spinal anesthesia. METHODS: in this prospective, randomized, double-blind study, 108 patients scheduled for hip fracture surgery under unilateral spinal anesthesia were enrolled to receive either 5 mg (group 1) or 7.5 mg (group 2) of hypobaric bupivacaine. Spinal anesthesia was performed in lateral position. Patients socio-demographic characteristics, hemodynamic profile, sensory and motor blocks parameters were recorded. RESULTS: both groups were comparable regarding to demographic data. Two cases of failure occurred in group 1 and one case in group 2 corresponding to a comparable efficiency rates (96.29% and 98.14% respectively; p = 0.5). A higher mean onset and lower mean regression times of sensory block were significantly noted in group 1 (7.79,3.76 min vs 5.75,2.35 min, p = 0.001 and 91.29,31.55 min vs 112.77,18.77 min, p =0.001 respectively). Incidence of bilateralization (29.62% vs 87.03%, p = 0.001), incidence of hypotensive episodes (59.25% vs 92.59%, p = 0.001) and vascular loading (1481.48,411.65 ml vs 2111.11,596.10 ml, p = 0.001) were significantly higher in group 2. CONCLUSION: the dosage of 5mg of hypobaric bupivacaine in unilateral spinal anesthesia is as effective as the dosage of 7.5 mg with lower bilateralization incidence and better hemodynamic stability. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English French |
| تدمد: | 1937-8688 |
| Relation: | https://www.panafrican-med-journal.com/content/article/28/108/pdf/108.pdf; https://doaj.org/toc/1937-8688 |
| DOI: | 10.11604/pamj.2017.28.108.11421 |
| URL الوصول: | https://doaj.org/article/dd583d6fb22e4730bef1b625603b6905 |
| رقم الانضمام: | edsdoj.583d6fb22e4730bef1b625603b6905 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19378688 |
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| DOI: | 10.11604/pamj.2017.28.108.11421 |