Academic Journal
Macrophage Activation Syndrome in Adults: A Retrospective Case Series
| العنوان: | Macrophage Activation Syndrome in Adults: A Retrospective Case Series |
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| المؤلفون: | Taylor Warmoth MD, Malvika Ramesh BS, Kenneth Iwuji MD, John S. Pixley MD |
| المصدر: | Journal of Investigative Medicine High Impact Case Reports, Vol 9 (2021) |
| بيانات النشر: | SAGE Publishing, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine (General) LCC:Pathology |
| مصطلحات موضوعية: | Medicine (General), R5-920, Pathology, RB1-214 |
| الوصف: | Macrophage activation syndrome (MAS) is a form of hemophagocytic lymphohistocytosis that occurs in patients with a variety of inflammatory rheumatologic conditions. Traditionally, it is noted in pediatric patients with systemic juvenile idiopathic arthritis and systemic lupus erythematous. It is a rapidly progressive and life-threatening syndrome of excess immune activation with an estimated mortality rate of 40% in children. It has become clear recently that MAS occurs in adult patients with underlying rheumatic inflammatory diseases. In this article, we describe 6 adult patients with likely underlying MAS. This case series will outline factors related to diagnosis, pathophysiology, and review present therapeutic strategies. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2324-7096 23247096 |
| Relation: | https://doaj.org/toc/2324-7096 |
| DOI: | 10.1177/23247096211026406 |
| URL الوصول: | https://doaj.org/article/57594102529044f6996e2e5d748ae839 |
| رقم الانضمام: | edsdoj.57594102529044f6996e2e5d748ae839 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23247096 |
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| DOI: | 10.1177/23247096211026406 |