Academic Journal
Scalable total synthesis of (+)-aniduquinolone A and its acid-catalyzed rearrangement to aflaquinolones
| العنوان: | Scalable total synthesis of (+)-aniduquinolone A and its acid-catalyzed rearrangement to aflaquinolones |
|---|---|
| المؤلفون: | Feng-Wei Guo, Xiao-Feng Mou, Yong Qu, Mei-Yan Wei, Guang-Ying Chen, Chang-Yun Wang, Yu-Cheng Gu, Chang-Lun Shao |
| المصدر: | Communications Chemistry, Vol 5, Iss 1, Pp 1-9 (2022) |
| بيانات النشر: | Nature Portfolio, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | Chemistry, QD1-999 |
| الوصف: | Quinolones can possess desirable antibacterial, antiviral and anticancer properties, rending them important synthetic targets for drug discovery purposes. Here, the gram-scale total synthesis of antiviral (+)-aniduquinolone A, possessing a 3,4-dioxygenated 5-hydroxy-4-aryl-quinolin-2(1H)-one skeleton, is reported, as well as its acid-catalyzed rearrangement to aflaquinolones A, C, and D. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2399-3669 |
| Relation: | https://doaj.org/toc/2399-3669 |
| DOI: | 10.1038/s42004-022-00655-x |
| URL الوصول: | https://doaj.org/article/56be7fb745554b98981f87d90c1bdcb0 |
| رقم الانضمام: | edsdoj.56be7fb745554b98981f87d90c1bdcb0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | ResultId |
1 |
|---|---|
| Header |
edsdoj Directory of Open Access Journals edsdoj.56be7fb745554b98981f87d90c1bdcb0 967 3 Academic Journal academicJournal 967.350158691406 |
| PLink |
https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsdoj&AN=edsdoj.56be7fb745554b98981f87d90c1bdcb0&custid=s6537998&authtype=sso |
| FullText |
Array
(
[Availability] => 0
)
Array ( [0] => Array ( [Url] => https://doaj.org/article/56be7fb745554b98981f87d90c1bdcb0 [Name] => EDS - DOAJ [Category] => fullText [Text] => View record in DOAJ [MouseOverText] => View record in DOAJ ) [1] => Array ( [Url] => https://resolver.ebscohost.com/openurl?custid=s6537998&groupid=main&authtype=ip,guest&sid=EBSCO:edsdoj&genre=article&issn=23993669&ISBN=&volume=5&issue=1&date=20220301&spage=1&pages=1-9&title=Communications Chemistry&atitle=Scalable%20total%20synthesis%20of%20%28%2B%29-aniduquinolone%20A%20and%20its%20acid-catalyzed%20rearrangement%20to%20aflaquinolones&id=DOI:10.1038/s42004-022-00655-x [Name] => Full Text Finder (s6537998api) [Category] => fullText [Text] => Full Text Finder [Icon] => https://imageserver.ebscohost.com/branding/images/FTF.gif [MouseOverText] => Full Text Finder ) ) |
| Items |
Array
(
[Name] => Title
[Label] => Title
[Group] => Ti
[Data] => Scalable total synthesis of (+)-aniduquinolone A and its acid-catalyzed rearrangement to aflaquinolones
)
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => <searchLink fieldCode="AR" term="%22Feng-Wei+Guo%22">Feng-Wei Guo</searchLink><br /><searchLink fieldCode="AR" term="%22Xiao-Feng+Mou%22">Xiao-Feng Mou</searchLink><br /><searchLink fieldCode="AR" term="%22Yong+Qu%22">Yong Qu</searchLink><br /><searchLink fieldCode="AR" term="%22Mei-Yan+Wei%22">Mei-Yan Wei</searchLink><br /><searchLink fieldCode="AR" term="%22Guang-Ying+Chen%22">Guang-Ying Chen</searchLink><br /><searchLink fieldCode="AR" term="%22Chang-Yun+Wang%22">Chang-Yun Wang</searchLink><br /><searchLink fieldCode="AR" term="%22Yu-Cheng+Gu%22">Yu-Cheng Gu</searchLink><br /><searchLink fieldCode="AR" term="%22Chang-Lun+Shao%22">Chang-Lun Shao</searchLink> ) Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => Communications Chemistry, Vol 5, Iss 1, Pp 1-9 (2022) ) Array ( [Name] => Publisher [Label] => Publisher Information [Group] => PubInfo [Data] => Nature Portfolio, 2022. ) Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2022 ) Array ( [Name] => Subset [Label] => Collection [Group] => HoldingsInfo [Data] => LCC:Chemistry ) Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => <searchLink fieldCode="DE" term="%22Chemistry%22">Chemistry</searchLink><br /><searchLink fieldCode="DE" term="%22QD1-999%22">QD1-999</searchLink> ) Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => Quinolones can possess desirable antibacterial, antiviral and anticancer properties, rending them important synthetic targets for drug discovery purposes. Here, the gram-scale total synthesis of antiviral (+)-aniduquinolone A, possessing a 3,4-dioxygenated 5-hydroxy-4-aryl-quinolin-2(1H)-one skeleton, is reported, as well as its acid-catalyzed rearrangement to aflaquinolones A, C, and D. ) Array ( [Name] => TypeDocument [Label] => Document Type [Group] => TypDoc [Data] => article ) Array ( [Name] => Format [Label] => File Description [Group] => SrcInfo [Data] => electronic resource ) Array ( [Name] => Language [Label] => Language [Group] => Lang [Data] => English ) Array ( [Name] => ISSN [Label] => ISSN [Group] => ISSN [Data] => 2399-3669 ) Array ( [Name] => NoteTitleSource [Label] => Relation [Group] => SrcInfo [Data] => https://doaj.org/toc/2399-3669 ) Array ( [Name] => DOI [Label] => DOI [Group] => ID [Data] => 10.1038/s42004-022-00655-x ) Array ( [Name] => URL [Label] => Access URL [Group] => URL [Data] => <link linkTarget="URL" linkTerm="https://doaj.org/article/56be7fb745554b98981f87d90c1bdcb0" linkWindow="_blank">https://doaj.org/article/56be7fb745554b98981f87d90c1bdcb0</link> ) Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsdoj.56be7fb745554b98981f87d90c1bdcb0 ) |
| RecordInfo |
Array
(
[BibEntity] => Array
(
[Identifiers] => Array
(
[0] => Array
(
[Type] => doi
[Value] => 10.1038/s42004-022-00655-x
)
)
[Languages] => Array
(
[0] => Array
(
[Text] => English
)
)
[PhysicalDescription] => Array
(
[Pagination] => Array
(
[PageCount] => 9
[StartPage] => 1
)
)
[Subjects] => Array
(
[0] => Array
(
[SubjectFull] => Chemistry
[Type] => general
)
[1] => Array
(
[SubjectFull] => QD1-999
[Type] => general
)
)
[Titles] => Array
(
[0] => Array
(
[TitleFull] => Scalable total synthesis of (+)-aniduquinolone A and its acid-catalyzed rearrangement to aflaquinolones
[Type] => main
)
)
)
[BibRelationships] => Array
(
[HasContributorRelationships] => Array
(
[0] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Feng-Wei Guo
)
)
)
[1] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Xiao-Feng Mou
)
)
)
[2] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Yong Qu
)
)
)
[3] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Mei-Yan Wei
)
)
)
[4] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Guang-Ying Chen
)
)
)
[5] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Chang-Yun Wang
)
)
)
[6] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Yu-Cheng Gu
)
)
)
[7] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Chang-Lun Shao
)
)
)
)
[IsPartOfRelationships] => Array
(
[0] => Array
(
[BibEntity] => Array
(
[Dates] => Array
(
[0] => Array
(
[D] => 01
[M] => 03
[Type] => published
[Y] => 2022
)
)
[Identifiers] => Array
(
[0] => Array
(
[Type] => issn-print
[Value] => 23993669
)
)
[Numbering] => Array
(
[0] => Array
(
[Type] => volume
[Value] => 5
)
[1] => Array
(
[Type] => issue
[Value] => 1
)
)
[Titles] => Array
(
[0] => Array
(
[TitleFull] => Communications Chemistry
[Type] => main
)
)
)
)
)
)
)
|
| IllustrationInfo |