التفاصيل البيبلوغرافية
| العنوان: |
Scalable total synthesis of (+)-aniduquinolone A and its acid-catalyzed rearrangement to aflaquinolones |
| المؤلفون: |
Feng-Wei Guo, Xiao-Feng Mou, Yong Qu, Mei-Yan Wei, Guang-Ying Chen, Chang-Yun Wang, Yu-Cheng Gu, Chang-Lun Shao |
| المصدر: |
Communications Chemistry, Vol 5, Iss 1, Pp 1-9 (2022) |
| بيانات النشر: |
Nature Portfolio, 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Chemistry |
| مصطلحات موضوعية: |
Chemistry, QD1-999 |
| الوصف: |
Quinolones can possess desirable antibacterial, antiviral and anticancer properties, rending them important synthetic targets for drug discovery purposes. Here, the gram-scale total synthesis of antiviral (+)-aniduquinolone A, possessing a 3,4-dioxygenated 5-hydroxy-4-aryl-quinolin-2(1H)-one skeleton, is reported, as well as its acid-catalyzed rearrangement to aflaquinolones A, C, and D. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2399-3669 |
| Relation: |
https://doaj.org/toc/2399-3669 |
| DOI: |
10.1038/s42004-022-00655-x |
| URL الوصول: |
https://doaj.org/article/56be7fb745554b98981f87d90c1bdcb0 |
| رقم الانضمام: |
edsdoj.56be7fb745554b98981f87d90c1bdcb0 |
| قاعدة البيانات: |
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