التفاصيل البيبلوغرافية
| العنوان: |
Hepatitis B in Senegal: A Successful Infant Vaccination Program but Urgent Need to Scale Up Screening and Treatment (ANRS 12356 AmBASS survey) |
| المؤلفون: |
Lauren Périères, Aldiouma Diallo, Fabienne Marcellin, Marie Libérée Nishimwe, El Hadji Ba, Marion Coste, Gora Lo, Philippe Halfon, Coumba Touré Kane, Gwenaëlle Maradan, Patrizia Carrieri, Assane Diouf, Yusuke Shimakawa, Cheikh Sokhna, Sylvie Boyer, ANRS 12356 AmBASS Survey Study Group |
| المصدر: |
Hepatology Communications, Vol 6, Iss 5, Pp 1005-1015 (2022) |
| بيانات النشر: |
Wolters Kluwer Health/LWW, 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: |
Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: |
Senegal introduced the infant hepatitis B virus (HBV) vaccination in 2004 and recently committed to eliminating hepatitis B by 2030. Updated epidemiological data are needed to provide information on the progress being made and to develop new interventions. We estimated the prevalence of hepatitis B surface antigen (HBsAg) in children and adults living in rural Senegal and assessed hepatitis B treatment eligibility. A cross‐sectional population‐based serosurvey of HBsAg was conducted in 2018‐2019 in a large sample (n = 3,118) of residents living in the Niakhar area (Fatick region, Senegal). Individuals positive for HBsAg subsequently underwent clinical and biological assessments. Data were weighted for age and sex and calibrated to be representative of the area’s population. Among the 3,118 participants, 206 were HBsAg positive (prevalence, 6.9%; 95% confidence interval [CI], 5.6‐8.1). Prevalence varied markedly according to age group in individuals aged 0‐4, 5‐14, 15‐34, and ≥35 years as follows: 0.0% (95% CI, 0.00‐0.01); 1.5% (95% CI, 0.0‐2.3); 12.4% (95% CI, 9.1‐15.6); and 8.8% (95% CI, 6.1‐11.5), respectively. Of those subsequently assessed, 50.9% (95% CI, 41.8‐60.0) had active HBV infection; 4 (2.9%; 95% CI, 0.9‐9.4) were eligible for hepatitis B treatment. Conclusion: In this first population‐based serosurvey targeting children and adults in rural Senegal, HBsAg prevalence was very low in the former, meeting the World Health Organization’s (WHO) |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2471-254X |
| Relation: |
https://doaj.org/toc/2471-254X |
| DOI: |
10.1002/hep4.1879 |
| URL الوصول: |
https://doaj.org/article/d5543feed2d34204a13f63f52a511d99 |
| رقم الانضمام: |
edsdoj.5543feed2d34204a13f63f52a511d99 |
| قاعدة البيانات: |
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