التفاصيل البيبلوغرافية
العنوان: |
Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival |
المؤلفون: |
Xi Lu, Naga Prathyusha Maturi, Malin Jarvius, Irem Yildirim, Yonglong Dang, Linxuan Zhao, Yuan Xie, E-Jean Tan, Pengwei Xing, Rolf Larsson, Mårten Fryknäs, Lene Uhrbom, Xingqi Chen |
المصدر: |
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022) |
بيانات النشر: |
Nature Portfolio, 2022. |
سنة النشر: |
2022 |
المجموعة: |
LCC:Science |
مصطلحات موضوعية: |
Science |
الوصف: |
The epigenetic regulation of glioblastoma stem cell (GSC) function remains poorly understood. Here, the authors compare the chromatin accessibility landscape of GSC cultures from mice and patients and suggest that the epigenome of GSCs is cell lineage-regulated and could predict patient survival. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-022-29912-2 |
URL الوصول: |
https://doaj.org/article/54f5b29285c34347a7324d03fb75af42 |
رقم الانضمام: |
edsdoj.54f5b29285c34347a7324d03fb75af42 |
قاعدة البيانات: |
Directory of Open Access Journals |