التفاصيل البيبلوغرافية
| العنوان: |
Lymph node ratio predicts recurrence-free survival and disease-specific survival of patients with pyriform sinus squamous cell carcinoma |
| المؤلفون: |
Yunhe Liu, Hui Huang, Jie Liu, Xiaolei Wang, Shaoyan Liu |
| المصدر: |
Asian Journal of Surgery, Vol 46, Iss 6, Pp 2277-2283 (2023) |
| بيانات النشر: |
Elsevier, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Surgery |
| مصطلحات موضوعية: |
Pyriform sinus cancer, Lymph node ratio (LNR), Recurrence-free survival, Disease-specific survival, Surgery, RD1-811 |
| الوصف: |
Objective: This study assessed positive lymph node ratio (LNR) as a prognostic marker for patients with pyriform sinus cancer. Methods: The present study retrospectively analyzed 101 patients with pyriform sinus cancer to determine the association of LNR with recurrence-free survival (RFS) and disease-specific survival (DSS). Results: The patients were followed up for a median duration of 28 months (range: 6–196 months). The number of median dissected lymph nodes (LNs) was 41, and the number of median positive LNs was three. The receiver operating characteristic curve revealed an LNR cut-off value of 8.6%. Lymphovascular invasion (LVI) or perineural invasion (PNI) (P = 0.001), thyroid gland invasion (TGI, P = 0.000), positive LNs >4 (P = 0.036), and LNR >8.6% (P = 0.008) were significantly associated with poor RFS, and LVI or PNI (P = 0.005), tumor pT3/T4 stage (P = 0.028), positive LNs >4 (P = 0.033), TGI (P = 0.001), and LNR >8.6% (P = 0.003) were significantly associated with poor DSS. The multivariate analysis revealed that LVI or PNI (P = 0.010), TGI (P = 0.000), and LNR >8.6% (P = 0.022) were independent predictors for poor RFS, while tumor pT3/T4 stage (P = 0.049), TGI (P = 0.015), and LNR >8.6% (P = 0.001) were independent predictors for poor DDS. Conclusion: LNR and other clinicopathological data can be used to predict the RFS and DSS of pyriform sinus cancer patients. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1015-9584 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1015958422013069; https://doaj.org/toc/1015-9584 |
| DOI: |
10.1016/j.asjsur.2022.09.048 |
| URL الوصول: |
https://doaj.org/article/54ec62512a084d1fb7ccd368ca86c0db |
| رقم الانضمام: |
edsdoj.54ec62512a084d1fb7ccd368ca86c0db |
| قاعدة البيانات: |
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