التفاصيل البيبلوغرافية
| العنوان: |
Phospholipid removal during degradation of rat plasma very low density lipoprotein in vitro1 |
| المؤلفون: |
S Eisenberg, D Schurr |
| المصدر: |
Journal of Lipid Research, Vol 17, Iss 6, Pp 578-587 (1976) |
| بيانات النشر: |
Elsevier, 1976. |
| سنة النشر: |
1976 |
| المجموعة: |
LCC:Biochemistry |
| مصطلحات موضوعية: |
heparin releasable hospholipase activity, lipoprotein-phospholipids, lysolecithin, [32P]lecithin, [32P]sphingomyelin, “hepatic” and “extrahepatic” lipoprotein lipase, Biochemistry, QD415-436 |
| الوصف: |
The hydrolysis of glycerophospholipids in very low density lipoprotein by enzyme(s) released into circulation after the injection of heparin to rats was studied. [32P]Lysolecithin was formed rapidly from [32P]lecithin when very low density lipoprotein, labeled biosynthetically with 32P, was incubated with postheparin plasma. The [32P]lysolecithin was associated with the plasma protein fraction of density greater than 1.21 g/ml, whereas [32P]lecithin exchanged between very low and high density lipoproteins. Inhibition of the plasma lecithin: cholesterol acyl transferase activity did not change the excess [32P]lysolecithin formation in postheparin plasma, and only a negligible amount of radioactivity was associated with blood cells when the incubation was repeated in whole blood.Analysis of the results has demonstrated that phospholipids are removed from VLDL by two pathways: hydrolysis of glycerophospholipids by the heparin-releasable phospholipase activity (>50%) and transfer to high density lipoproteins ( |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
0022-2275 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S0022227520417298; https://doaj.org/toc/0022-2275 |
| DOI: |
10.1016/S0022-2275(20)41729-8 |
| URL الوصول: |
https://doaj.org/article/542b9ba7769a425baa4c97ba81010f82 |
| رقم الانضمام: |
edsdoj.542b9ba7769a425baa4c97ba81010f82 |
| قاعدة البيانات: |
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