Academic Journal
PrOgnosis in Pulmonary Embolism (PoPE): 30-Day mortality risk score based on five admission parameters
العنوان: | PrOgnosis in Pulmonary Embolism (PoPE): 30-Day mortality risk score based on five admission parameters |
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المؤلفون: | Filipa Gerardo, Daniel Faria, Pedro Silvério António, João Baltazar Ferreira, Marco Beringuilho, Hilaryano Ferreira, Inês Fialho, Inês Miranda, Yolanda Sá Pereira, Afonso Nunes-Ferreira, David Roque, Miguel B. Santos, Carlos Morais, Sérgio Bravo Baptista, João B. Augusto |
المصدر: | Revista Portuguesa de Cardiologia, Vol 43, Iss 1, Pp 1-8 (2024) |
بيانات النشر: | Elsevier, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
مصطلحات موضوعية: | Embolia pulmonar, Mortalidade, Prognóstico, Score de risco, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
الوصف: | Introduction and objective: Several scoring systems have been developed for risk stratification in patients with acute pulmonary embolism (PE). The Pulmonary Embolism Severity Index (PESI) and its simplified version (sPESI) are among the most used, however the high number of variables hinder its application. Our aim was to derive an easy-to-perform score based on simple parameters obtained at admission to predict 30-day mortality in acute PE patients. Methods: Retrospective study in 1115 patients with acute PE from two institutions (derivation cohort n=835, validation cohort n=280). The primary endpoint was all-cause mortality at 30 days. Statistically and clinically relevant variables were selected for multivariable Cox regression analysis. We derived and validated a multivariable risk score model and compared to other established scores. Results: The primary endpoint occurred in 207 patients (18.6%). Our model included five variables weighted as follows: modified shock index ≥1.1 (hazard ratio [HR] 2.57, 1.68–3.92, p1,1 (HR 2,57, 1,68-3,92, p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English Portuguese |
تدمد: | 0870-2551 |
Relation: | http://www.sciencedirect.com/science/article/pii/S0870255123003761; https://doaj.org/toc/0870-2551 |
DOI: | 10.1016/j.repc.2023.04.011 |
URL الوصول: | https://doaj.org/article/53b5b6bbc2a94bf8a27d92a5ecea87a6 |
رقم الانضمام: | edsdoj.53b5b6bbc2a94bf8a27d92a5ecea87a6 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 08702551 |
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DOI: | 10.1016/j.repc.2023.04.011 |