Academic Journal
Synthesis, structural characterization and cytotoxic activity of two new organoruthenium(II) complexes
| العنوان: | Synthesis, structural characterization and cytotoxic activity of two new organoruthenium(II) complexes |
|---|---|
| المؤلفون: | Grgurić-Šipka Sanja, Alshtewi Arbi Mohamed Al.M., Jeremić Dejan, Kaluđerović Goran N., Gómez-Ruiz Santiago, Žižak Željko, Juranić Zorica, Sabo Tibor J. |
| المصدر: | Journal of the Serbian Chemical Society, Vol 73, Iss 6, Pp 619-630 (2008) |
| بيانات النشر: | Serbian Chemical Society, 2008. |
| سنة النشر: | 2008 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | ruthenium(ii) complexes, p-cymene, k3-thiosemicarbazone, n-methylpiperazine, cytotoxic activity, Chemistry, QD1-999 |
| الوصف: | Two new p-cymene ruthenium(II) complexes containing as additional ligands N-methylpiperazine ([(η6-p-cymene)RuCl2(CH3NH(CH2)4NH)]PF6, complex 1) or vitamin K3-thiosemicarbazone ([(η6-p-cymene)RuCl2(K3tsc)], complex 2) were synthesized starting from [(η6-p-cymene)2RuCl2]2 and the corresponding ligand. The complexes were characterized by elemental analysis, IR, electronic absorption and NMR spectroscopy. The X-ray crystal structure determination of complex 1 revealed “piano-stool” geometry. The differences in the cytotoxic activity of the two complexes are discussed in terms of the ligand present. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0352-5139 1820-7421 |
| Relation: | https://doaj.org/toc/0352-5139; https://doaj.org/toc/1820-7421 |
| DOI: | 10.2298/JSC0806619G |
| URL الوصول: | https://doaj.org/article/531065dcd27d4f9daa0a4e96e18672ee |
| رقم الانضمام: | edsdoj.531065dcd27d4f9daa0a4e96e18672ee |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 03525139 18207421 |
|---|---|
| DOI: | 10.2298/JSC0806619G |