Academic Journal
The association between systemic inflammatory response index and contrast-associated acute kidney injury in patients undergoing elective percutaneous coronary intervention
| العنوان: | The association between systemic inflammatory response index and contrast-associated acute kidney injury in patients undergoing elective percutaneous coronary intervention |
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| المؤلفون: | Jun-Han Chen, Li-Wei Zhang, Wen-Jia Liang, Wei-ze Lin, Xiao-Fang Chen, Zhi-Jie Lin, Chang-Xi Wang, Kai-Yang Lin, Yan-Song Guo |
| المصدر: | Renal Failure, Vol 46, Iss 1 (2024) |
| بيانات النشر: | Taylor & Francis Group, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | Systemic inflammatory response index, contrast-associated acute kidney injury, mortality, percutaneous coronary intervention, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | Background The systemic inflammatory response index (SIRI), served as a novel inflammatory biomarker, is the synthesis of neutrophils, monocytes and lymphocytes.Aims We hypothesized that SIRI has predictive value for contrast-associated acute kidney injury (CA-AKI) and long-term mortality in patients undergoing elective percutaneous coronary intervention (PCI).Methods We retrospectively observed 5685 patients undergoing elective PCI from January 2012 to December 2018. Venous blood samples were collected to obtain the experimental data on the day of admission or the morning of the next day. SIRI = neutrophil count × monocyte count/lymphocyte count. CA-AKI was defined as an increase of 50% or 0.3 mg/dl in SCr from baseline within 48 h after contrast exposure.Results The incidence of CA-AKI was 6.1% (n = 352). The best cutoff value of SIRI for predicting CA-AKI was 1.39, with a sensitivity of 52.3% and a specificity of 67.3%. [AUC: 0.620, 95% confidence interval (CI): 0.590–0.651, p 1.39) was a strong independent predictor of CA-AKI in patients undergoing elective PCI compared with the low SIRI group (SIRI ≤ 1.39) (odds ratio = 1.642, 95% CI: 1.274–2.116, p 1.39 was significantly associated with long-term mortality at a median follow-up of 2.8 years. [Hazard ratio (HR)=1.448, 95%CI: 1.188–1.765; p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0886022X 1525-6049 0886-022X |
| Relation: | https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049 |
| DOI: | 10.1080/0886022X.2024.2330621 |
| URL الوصول: | https://doaj.org/article/e530c5b7795241f7986e0fecf58fab37 |
| رقم الانضمام: | edsdoj.530c5b7795241f7986e0fecf58fab37 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 0886022X 15256049 |
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| DOI: | 10.1080/0886022X.2024.2330621 |