Academic Journal

Efficacy of Pfizer-BioNTech in SARS-CoV-2 Delta cluster

التفاصيل البيبلوغرافية
العنوان: Efficacy of Pfizer-BioNTech in SARS-CoV-2 Delta cluster
المؤلفون: Hannah E. Landsberg, MSN, MPH, Jacquelyn Turcinovic, B.S., Madison Sullivan, MPH, John H. Connor, Ph.D., Davidson H. Hamer, MD, Judy T. Platt, MD
المصدر: International Journal of Infectious Diseases, Vol 114, Iss , Pp 62-64 (2022)
بيانات النشر: Elsevier, 2022.
سنة النشر: 2022
المجموعة: LCC:Infectious and parasitic diseases
مصطلحات موضوعية: COVID-19, Sequencing, Delta variant, Variant of concern, PCR testing, Contact tracing, Infectious and parasitic diseases, RC109-216
الوصف: ABSTRACT: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) sublineage B.1.617.2 or Delta, a variant that began circulating in India and is becoming dominant in the USA, has been responsible for significant morbidity and mortality. In May 2021, the Delta variant was upgraded to a variant of concern by international authorities. This article reports a cluster of SARS-CoV-2 Delta cases detected in Boston, Massachusetts, in May 2021 involving a recent traveller from India and subsequent transmission to two of three close contacts. All three close contacts experienced the same primary exposure events but differed in vaccination status. The two close contacts that eventually tested positive were unvaccinated. The other close contact had received one dose of the BNT162b (Pfizer-BioNTech) vaccine prior to exposure, and received their second dose 2 days after exposure. This case series illustrates the effectiveness of partial vaccination in blocking transmission of the Delta variant to vaccinated individuals under circumstances where the probability of transmission for unvaccinated individuals is high.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1201-9712
Relation: http://www.sciencedirect.com/science/article/pii/S1201971221008407; https://doaj.org/toc/1201-9712
DOI: 10.1016/j.ijid.2021.10.053
URL الوصول: https://doaj.org/article/52bd5f1be98c4a7b8d31ec631ce2ec32
رقم الانضمام: edsdoj.52bd5f1be98c4a7b8d31ec631ce2ec32
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:12019712
DOI:10.1016/j.ijid.2021.10.053